白介素11(IL11)活性蛋白

Active Interleukin 11 (IL11)

AGIF; Adipogenesis Inhibitory Factor; Oprelvekin

  • 白介素11(IL11)活性蛋白 产品包装(模拟)
  • 白介素11(IL11)活性蛋白 产品包装(模拟)
  • APA057Hu61.png Figure. SDS-PAGE
  • 白介素11(IL11)活性蛋白 Sample: Recombinant IL11, Human;
    Antibody: Rabbit Anti-Human IL11 Ab (PAA057Hu06)
    Figure. Western Blot
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

活性实验

Interleukin 11 (IL-11) is a multifunctional cytokine. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation IL-11 causes bone-resorption. Besides, IL-11 have been proved can promote migration of A549 cells, 5×104 cells were seeded into 6 well plates. After cell confluent, replace with DMEM without serum overnight. Using a (yellow) pipette tip make a straight scratch, simulating a wound, then washing the wells three times with PBS. Adding 1% serum standard DMEM containing various concentrations of recombinan human IL-11 to each well, incubating the plate for 48 hours at 37℃, 5% CO2. The results observed by inverted microscope was shown in Figure.
(A) A549 cells cultured in DMEM with 100ng/mL IL-11 for 48h;
(B) A549 cells cultured in DMEM before addition IL-11.
Figure. Wound healing assay of A549 cells after stimulated with IL-11.

用法

Reconstitute in 20mM Tris, 150mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

储存

避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

相关产品

编号 适用物种:Homo sapiens (Human,人) 应用(仅供研究使用,不用于临床诊断!)
EPA057Hu61 白介素11(IL11)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APA057Hu01 白介素11(IL11)活性蛋白 Cell culture; Activity Assays.
EPA057Hu62 白介素11(IL11)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA057Hu01 白介素11(IL11)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APA057Hu62 白介素11(IL11)活性蛋白 Cell culture; Activity Assays.
APA057Hu61 白介素11(IL11)活性蛋白 Cell culture; Activity Assays.
PAA057Hu01 白介素11(IL11)多克隆抗体 WB; IHC; ICC; IP.
MAA057Hu22 白介素11(IL11)单克隆抗体 WB; IHC; ICC; IP.
MAA057Hu21 白介素11(IL11)单克隆抗体 WB; IHC; ICC; IP.
SEA057Hu 白介素11(IL11)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA057Hu 白介素11(IL11)等多因子检测试剂盒(流式荧光发光法) FLIA Assay for Antigen Detection.

参考文献

杂志 参考文献
Molecular Medicine Reports Regulatory effect of chemerin and therapeutic efficacy of chemerin‑9 in pancreatogenic diabetes mellitus [Pubmed: 31922216]
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