3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)多克隆抗体
Polyclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR)
HMG-CoA Reductase; Hydroxymethylglutaryl-CoA Reductase
- 编号PAD686Ra01
- 物种Rattus norvegicus (Rat，大鼠) 相同的名称，不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 RPD686Ra01-3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)重组蛋白
- 缓冲液成份0.01M 磷酸盐缓冲液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性状液体
- 浓度0.5mg/ml
- 且适物种Sus scrofa; Porcine (Pig，猪)
- 应用WB; IHC; ICC; IP.
如果抗体需用于流式细胞术，请参见流式抗体。 - 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 684 ¥ 1596 ¥ 2280 ¥ 5700 ¥ 22800
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产品包装(模拟)
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产品包装(模拟)
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DAB staining on IHC-P; Samples: Rat Colon Tissue; Primary Ab: 20μg/ml Rabbit Anti-Rat HMGCR Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
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DAB staining on IHC-P;
Samples: Rat Cardiac Muscle Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Rat HMGCR Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19) -
DAB staining on IHC-P;
Samples: Rat Liver Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Rat HMGCR Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19) -
DAB staining on IHC-P;
Sample: Porcine Liver Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Rat HMGCR Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19) -
DAB staining on IHC-P;
Sample: Porcine Colon Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Rat HMGCR Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19) -
DAB staining on IHC-P;
Sample: Porcine Cardiac Muscle Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Rat HMGCR Antibody
Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
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Figure. Western Blot; Sample: Recombinant HMGCR, Rat.
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通过ISO 9001、ISO 13485质量体系认证
特异性
该抗体是针对HMGCR的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别HMGCR。
用法
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种：Rattus norvegicus (Rat，大鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| RPD686Ra01 | 3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAD686Ra01 | 3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)多克隆抗体 | WB; IHC; ICC; IP. |
| MAD686Ra21 | 3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)单克隆抗体 | WB; IHC; ICC; IP. |
| SED686Ra | 3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMD686Ra | 3-羟基3-甲基戊二酰辅酶A还原酶(HMGCR)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Neuroscience | 27-Hydroxycholesterol contributes to disruptive effects on learning and memory by modulating cholesterol metabolism in the rat brain [PubMed: 25987203] |
| Neurotoxicology. | 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. [pubmed:28167099] |
| archives of medical research | Transthyretin Regulated by linc00657/miR-205-5p Promoted Cholesterol Metabolism by Inducing SREBP2-HMGCR and Inhibiting LXRα-CYP7A1 [Pubmed: 32241558] |
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