粘蛋白5AC(MUC5AC)多克隆抗体

Polyclonal Antibody to Mucin 5 Subtype AC (MUC5AC)

TBM; MUC5; LeB; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtypes A And C,Tracheobronchial/Gastric; Gastric mucin; Lewis B blood group antigen; Major airway glycoprotein

  • 粘蛋白5AC(MUC5AC)多克隆抗体 产品包装(模拟)
  • 粘蛋白5AC(MUC5AC)多克隆抗体 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对MUC5AC的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别MUC5AC。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Bos taurus; Bovine (Cattle，牛) 应用(仅供研究使用，不用于临床诊断！)
PAA756Bo01 粘蛋白5AC(MUC5AC)多克隆抗体 WB; IHC; ICC; IP.

参考文献

杂志 参考文献
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Cell & Molecular Biology Role of aquaporin 5 in antigen-induced airway inflammation and mucous hyperproduction in mice [PubMed: 20550619]
Mucosal Immunology Homeostatic control of conjunctival mucosal goblet cells by NKT-derived IL-13 [Nature: 201082a]
European Journal of Pharmacology Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways [ScienceDirect: S0014299912005523]
PLoS One Baicalein Reduces Airway Injury in Allergen and IL-13 Induced Airway Inflammation [PubMed: PMC3639905]
Respiratory Researh Pyocyanin-induced mucin production is associated with redox modification of FOXA2 [PubMed: PMC3765780]
Surgery A novel serum marker for biliary tract cancer: Diagnostic and prognostic values of quantitative evaluation of serum mucin 5AC (MUC5AC) [Pubmed: 24468034]
Biochemical and Biophysical Research Communications The human cathelicidin LL-37 enhances airway mucus production in chronic obstructive pulmonary disease [Pubmed:24291709]
Journal of Proteomics Proteomic analysis of cancer and mesothelial cells reveals an increase in Mucin 5AC during ovarian cancer and peritoneal interaction [Pubmed:24726482]
Experimental Lung Research The human Cathelicidin LL-37 induces MUC5AC mucin production by airway epithelial cells via TACE-TGF-α-EGFR pathway [Pubmed:24901072]
Surgery.? Assessment of bile and serum mucin5AC in cholangiocarcinoma: Diagnostic performance and biologic significance [Pubmed:25151557]
Allergology International Leukotriene E 4 induces MUC5AC release from human airway epithelial NCI-H292 cells [Pubmed:25838093]
Respirology Secreted mucins and airway bacterial colonization in non-CF bronchiectasis [PubMed: 26172851]
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International Immunopharmacology Clarithromycin inhibits TNF-α-induced MUC5AC mucin gene expression via the MKP-1-p38MAPK-dependent pathway [pubmed:28550735]
Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой [10.20538/1682-0363-2017-2-146-158]
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Chemotherapy Oxytetracycline Inhibits Mucus Secretion and Inflammation in Human Airway Epithelial Cells. [pubmed:28578323]
Allergy Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps [Pubmed:29802623]
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Inflammation Plantamajoside Inhibits Lipopolysaccharide-Induced MUC5AC Expression and Inflammation through Suppressing the PI3K/Akt and NF-κB Signaling Pathways in … [Pubmed:29349683]
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Clinical and Experimental Ophthalmology Development of a highly sensitive and reliable enzyme-linked immunosorbent assay for MUC5aC in human tears extracted from schirmer strips [Pubmed: 30214141]
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Phytomedicine Regulation effects of naringin on diesel particulate matter-induced abnormal airway surface liquid secretion [Pubmed: 31301536]
Scientific Reports Regional comparison of Goblet cell number and Area in exposed and covered Dry eyes and their Correlation with Tear MUC5AC [Pubmed: 32076085]
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Less Airway Inflammation and Goblet Cell Metaplasia in an IL-33-Induced Asthma Model of Leptin-Deficient Obese Mice []
Exp Mol Pathol The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal?¡­ [33285209]
FEBS Open Bio Porphyromonas gingivalis gingipains potentially affect MUC5AC gene expression and protein levels in respiratory epithelial cells [33332733]
Cell Rep Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs [33535050]
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