白介素1β(IL1b)检测试剂盒(酶联免疫吸附试验法)

ELISA Kit for Interleukin 1 Beta (IL1b)

IL1-B; IL1-Beta; IL1F2; IL-1β; Interleukin-1 Family Member 2; Catabolin

  • 白介素1β(IL1b)检测试剂盒(酶联免疫吸附试验法) 产品包装(模拟)
  • 白介素1β(IL1b)检测试剂盒(酶联免疫吸附试验法) 产品包装(模拟)
  • 白介素1β(IL1b)检测试剂盒(酶联免疫吸附试验法) 实验结果图
  • SEA563Ga.jpg 标准曲线图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

本试剂盒用于检测白介素1β(IL1b),经检测与其它相似物质无明显交叉反应。
由于受到技术及样本来源的限制,不可能完成对所有相关或相似物质交叉反应检测,因此本试剂盒有可能与未经检测的其它物质有交叉反应。

回收率

分别于定值血清及血浆样本中加入一定量的白介素1β(IL1b)(加标样品),重复测定并计算其均值,回收率为测定值与理论值的比率。

样本 回收率范围(%) 平均回收率(%)
serum(n=5) 79-94 90
EDTA plasma(n=5) 90-99 93
heparin plasma(n=5) 93-105 96

精密度

精密度用样品测定值的变异系数CV表示。CV(%) = SD/mean×100
批内差:取同批次试剂盒对低、中、高值定值样本进行定量检测,每份样本连续测定20 次,分别计算不同浓度样本的平均值及SD值。
批间差:选取3个不同批次的试剂盒分别对低、中、高值定值样本进行定量测定,每个样本使用同一试剂盒重复测定8次,分别计算不同浓度样本的平均值及SD值。
批内差: CV<10%
批间差: CV<12%

线性

在定值血清及血浆样本内加入适量的白介素1β(IL1b),并倍比稀释成1:2,1:4,1:8,1:16的待测样本,线性范围即为稀释后样本中白介素1β(IL1b)含量的测定值与理论值的比率。

样本 1:2 1:4 1:8 1:16
serum(n=5) 91-101% 78-101% 78-88% 85-103%
EDTA plasma(n=5) 78-102% 79-91% 78-104% 84-104%
heparin plasma(n=5) 96-104% 83-94% 78-89% 88-97%

稳定性

经测定,试剂盒在有效期内按推荐温度保存,其活性降低率小于5%。
为减小外部因素对试剂盒破坏前后检测值的影响,实验室的环境条件需尽量保持一致,尤其是实验室内温度、湿度及温育条件。其次由同一实验员来进行操作可减少人为误差。

试剂盒内容

试剂名称 数量 试剂名称 数量
96孔板(预包被) 1 96孔板覆膜 4
标准品 2 标准品稀释液 1×20mL
检测溶液A 1×120µL 检测稀释液A 1×12mL
检测溶液B 1×120µL 检测稀释液B 1×12mL
TMB底物 1×9mL 终止液 1×6mL
浓洗涤液 (30 × concentrate) 1×20mL 说明书 1

实验流程

1. 实验前标准品、试剂及样本的准备;
2. 加样(标准品及样本)100µL,37°C孵育1小时;
3. 吸弃,加检测溶液A100µL,37°C孵育1小时;
4. 洗板3次;
5. 加检测溶液B100µL,37°C孵育30分钟;
6. 洗板5次;
7. 加TMB底物90µL,37°C孵育10-20分钟;
8. 加终止液50µL,立即450nm读数。

ELISA Kit for Interleukin 1 Beta (IL1b)

实验原理

将白介素1β(IL1b)抗体包被于96孔微孔板中,制成固相载体,向微孔中分别加入标准品或标本,其中的白介素1β(IL1b)与连接于固相载体上的抗体结合,然后加入生物素化的白介素1β(IL1b)抗体,将未结合的生物素化抗体洗净后,加入HRP标记的亲和素,再次彻底洗涤后加入TMB底物显色。TMB在过氧化物酶的催化下转化成蓝色,并在酸的作用下转化成最终的黄色。颜色的深浅和样品中的白介素1β(IL1b)呈正相关。用酶标仪在450nm波长下测定吸光度(O.D.值),计算样品浓度。

相关产品

编号 适用物种:Chicken (Gallus,鸡) 应用(仅供研究使用,不用于临床诊断!)
RPA563Ga02 白介素1β(IL1b)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA563Ga01 白介素1β(IL1b)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA563Ga01 白介素1β(IL1b)多克隆抗体 WB; IHC; ICC; IP.
MAA563Ga21 白介素1β(IL1b)单克隆抗体 WB; IHC; ICC; IP.
SEA563Ga 白介素1β(IL1b)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.

参考文献

杂志 参考文献
Respiration Protective Effect of Nicotine on Lipopolysaccharide-Induced Acute Lung Injury in Mice [Karger: 000319151]
Experimental Gerontology Prophylactic lithium alleviates postoperative cognition impairment by phosphorylating hippocampal glycogen synthase kinase-3β (Ser9) in aged rats [ScienceDirect: S0531556511002373]
New Zealand Veterinary Journal Dominant expression of interleukin-8 vs interleukin-1β and tumour necrosis factor alpha in lungs of lambs experimentally infected with Mannheimia haemolytica. [Tandfonline: 596180]
The Journal of Urology Improvement by Phytotherapeutic Agent of Detrusor Overactivity, Down-Regulation of Pharmacological Receptors and Urinary Cytokines in Rats with Cyclophosphamide Induced Cystitis [PubMed: S0022534712049087]
Journal of Periodontology Online The Effect of Radachlorin-Mediated Antimicrobial Photodynamic Therapy on Clinical Parameters and Cytokine Profile in Ligature-Induced Periodontitis in Dogs [PubMed: 22813345]
PLoS One Recombinant Adiponectin Ameliorates Liver Ischemia Reperfusion Injury via Activating the AMPK/eNOS Pathway [PubMed: PMC3676360]
Lower Urinary Tract Symptoms Effects of Saw Palmetto Extract on Urodynamic Parameters, Bladder Muscarinic and Purinergic Receptors and Urinary Cytokines in Rats with Cyclophosphamide-Induced Cystitis [Onlinelibrary: luts.12015]
PLoS ONE A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches [Plosone: Source]
Journal of natural remedies Ixora coccinea down Regulate the Inflammation-Associated Prostaglandins (PGE-2), Nitric Oxide (NO) and Cytokines Production in LPS-Stimulated RAW 264.7 Macrophage [Jnronline: Source]
The Veterinary Journal Quantitative assessment of hsp70, IL-1β and TNF-α in the spinal cord of dogs with E40K SOD1-associated degenerative myelopathy [Pubmed: 24662024]
British Journal of Nutrition n-6: n-3 PUFA ratio is involved in regulating lipid metabolism and inflammation in pigs [Pubmed: 23947577]
AGE Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells [Pubmed: 24687841]
Inflamm Res. Intracranial injection of recombinant stromal-derived factor-1 alpha (SDF-1α) attenuates traumatic brain injury in rats. [Pubmed: 24352531]
Journal of Clinical Periodontology Experimental peri-implant mucositis at different implant surfaces. [Pubmed: 24521508]
Physiological Research Budesonide added to modified porcine surfactant Curosurf may additionally improve the lung functions in meconium aspiration syndrome. [Pubmed: 2432969]
International immunopharmacology Ruscogenin attenuates monocrotaline-induced pulmonary hypertension in rats [Pubmed: 23538027]
Journal of Pharmaceutical Sciences and Pharmacology Anti-inflammatory Effect of Euphorbia hirta Leaf Extract in Rats and Modulation of Inflammation-Associated Prostaglandins (PGE-2) and Nitric Oxide (NO) Expression in RAW264.7 Macrophage [Ingentaconnect: Source]
Mediators of Inflammation Protective Effects of Pretreatment with Oleanolic Acid in Rats in the Acute Phase of Hepatic Ischemia-Reperfusion Injury: Role of the PI3K/Akt Pathway [Hindawi: 451826]
Journal of Periodontology Effects of Photodynamic Therapy on the Clinical and Gingival Crevicular Fluid Inflammatory Biomarkers in Chronic Periodontitis: A Split-Mouth Randomized Clinical Trial [Joponline: 130464]
Antimicrobial Agents and Chemotherapy The antimicrobial peptide OH-CATH30 as a potential therapy for antibiotic-resistant Pseudomonas aeruginosa keratitis [Asm:Source]
INTERNATIONAL JOURNAL OF MEDICINE AND MEDICAL RESEARCH L-ARGININE, BUT NOT L-NAME PROTECTS AGAINST LIVER INJURY INDUCED BY EXPERIMENTAL ISCHEMIA-REPERFUSION [Tdmu:Source]
Basic &amp; Clinical Pharmacology &amp; Toxicology Treatment with Carnitine Enhances Bone Fracture Healing under Osteoporotic and/or Inflammatory Conditions [Wiley:Source]
Evidence-Based Complementary and Alternative Medicine Ginsenosides Rg1 from Panax ginseng: A Potential Therapy for Acute Liver Failure Patients? [Pubmed:Pmc4241314]
Nucleic Acids Res. MRTF-A steers an epigenetic complex to activate endothelin-induced pro-inflammatory transcription in vascular smooth muscle cells [Pubmed:Pmc4176337]
Cell Death Dis. MicroRNA-30d regulates cardiomyocyte pyroptosis by directly targeting foxo3a in diabetic cardiomyopathy [Pubmed:Pmc4237254]
Inflamm Res. Intracranial injection of recombinant stromal-derived factor-1 alpha (SDF-1α) attenuates traumatic brain injury in rats [Pubmed:24352531]
J Clin Periodontol. Experimental peri‐implant mucositis at different implant surfaces [Pubmed:24521508]
Inflammation Effects of honokiol on sepsis-induced acute kidney injury in an experimental model of sepsis in rats [Pubmed:24531855]
Antimicrob Agents Chemother. Therapeutic potential of the antimicrobial peptide OH-CATH30 for antibiotic-resistant Pseudomonas aeruginosa keratitis [Pubmed:24637683]
British Journal of Nutrition Grape seed extract supplementation attenuates the heat stress-induced responses of jejunum epithelial cells in Simmental?×?Qinchuan steers [Pubmed:24846452]
J Surg Res. Valproic acid protects septic mice from renal injury by reducing the inflammatory response [Pubmed:24948542]
Inflammation.? Alpha-lipoic acid exerts anti-inflammatory effects on lipopolysaccharide-stimulated rat mesangial cells via inhibition of nuclear factor kappa B (NF-κB) signaling pathway. [Pubmed:24962643]
Archives of Oral Biology Hyperlipidemia causes changes in inflammatory responses to periodontal pathogen challenge: Implications in acute and chronic infections [Pubmed:24992577]
Investigative ophthalmology &amp; visual science TSG-6 Protects Corneal Endothelium From Transcorneal Cryoinjury in Rabbits [Pubmed:25034606]
Connective Tissue Research Metabolic and cytoprotective effects of in vivo peri-patellar hyaluronic acid injections in cultured tenocytes [Pubmed:25333747]
Oncotarget Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils [Pubmed:25347345]
Molecular Medicine Reports GYY4137, a hydrogen sulfide‑releasing molecule, inhibits the inflammatory response by suppressing the activation of nuclear factor‑kappa B and mitogen‑activated protein kinases in Coxsackie virus B3‑infected rat cardiomyocytes. [Pubmed:25377925]
Neural Regen Res.? Inflammatory response and neuronal necrosis in rats with cerebral ischemia [Pubmed:25422636]
International Immunopharmacology NF-κB activation and proinflammatory cytokines mediated protective effect of Indigofera caerulea Roxb. on CCl 4 induced liver damage in rats [Pubmed:25445959]
Journal of Surgical Research Ursolic acid improves survival and attenuates lung injury in septic rats induced by cecal ligation and puncture [Pubmed:25454976]
Journal of Surgical Research Melatonin attenuates intestinal ischemia–reperfusion-induced lung injury in rats by upregulating N-myc downstream-regulated gene 2 [Pubmed:25491174]
Journal of Translational Medicine Protective effects of astaxanthin against ischemia/reperfusion induced renal injury in mice [Pubmed:25623758]
Molecular Medicine Reports Tanshinone ⅡA attenuates bleomycin-induced pulmonary fibrosis in rats [Pubmed:25672255]
International Journal of Clinical and Experimental Pathology Panax notoginseng saponins promote wound repair of anterior cruciate ligament through phosphorylation of PI3K, AKT and ERK [Pubmed:25755732]
Mediators of Inflammation Effect of TLR4/MyD88 Signaling Pathway on Expression of IL-1β and TNF-α in Synovial Fibroblasts from Temporomandibular Joint Exposed to Lipopolysaccharide [Pubmed:25810567]
Int J Clin Exp Pathol Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis [PubMed: 26191125]
Clinical and Experimental Pharmacology and Physiology Curcumin alleviates lung injury in diabetic rats by inhibiting nuclear factor‐κB pathway [PubMed: 26111829]
Drug Des Devel Ther Cardioprotection against ischemia/reperfusion injury by QiShenYiQi Pill [PubMed: 26109848]
Endocrine Journal Relationship between serum secreted frizzled-related protein 4 levels and the first-phase of glucose-stimulated insulin secretion in individuals with different glucose tolerance [PubMed: 26041556]
Int J Clin Exp Pathol Effects of dexmedetomidine on the protection of hyperoxia-induced lung injury in newborn rats [PubMed: 26261523]
Biomed Res Int Basic Fibroblast Growth Factor Ameliorates Endothelial Dysfunction in Radiation-Induced Bladder Injury [PubMed: 26351640]
Front Pharmacol Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats [PubMed: 26483688]
Mol Med Rep Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin [PubMed: 25760938]
Life Sci Betulin attenuates kidney injury in septic rats through inhibiting TLR4/NF-κB signaling pathway [PubMed: 26656467]
Asian Pac J Trop Med Effect of SecinH3 on lung injury induced by sepsis of rats [PubMed: 26706678]
PLOS ONE Penehyclidine Hydrochloride Preconditioning Provides Cardioprotection in a Rat Model of Myocardial Ischemia/Reperfusion Injury [PubMed: 26632817]
Int Immunopharmacol Betulin attenuates lung and liver injuries in sepsis [PubMed: 26644168]
Journal of Histochmistry and Cytochmistry Epigallocatechin-3-Gallate Attenuates Unilateral Ureteral Obstruction-Induced Renal Interstitial Fibrosis in Mice [PubMed: 25549657]
J Histochem Cytochem Glycyrrhizic Acid Prevents Sepsis-Induced Acute Lung Injury and Mortality in Rats [PubMed: 26385569]
Anim Reprod Sci. Alteration in peripheral blood concentration of certain pro-inflammatory cytokines in cows developing retention of fetal membranes [PubMed: 25851495]
Cell Physiol Biochem MicroRNA-155 Promotes Atherosclerosis Inflammation via Targeting SOCS1 [PubMed: 26159489]
Journal of Medicinal Food A Standardized Extract of [PubMed: 26501382]
journal of veterinary science Autologous processed plasma: cytokine profile and effects upon injection into healthy equine joints [PubMed: 25269714]
Clin Exp Pharmacol Physiol Silymarin attenuates paraquat-induced lung injury via Nrf2-mediated pathway in vivo and in vitro [PubMed: 26173462]
Immunologic Research Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE2 and is crucial for liver transplant tolerance [PubMed: 25982496]
Journal of Surgical Research Cyanidin-3-O-glucoside attenuates acute lung injury in sepsis rats [PubMed: 26152793]
Life Sciences Neuroprotective effect of allicin in a rat model of acute spinal cord injury [PubMed: 26546416]
International Journal of Immunopathology & Pharmacology Sea buckthorn (Hippophae rhamnoides L.) oil protects against chronic stress-induced inhibitory function of natural killer cells in rats [PubMed: 26684638]
Arquivos Brasileiros de Oftalmologia Effects of morphine on the expression of cytokines and inflammatory mediators in a rabbit model of endotoxin-induced experimental uveitis [PubMed: 26677041]
Neuropeptides Melanocortin MC6 receptor agonists alleviate brain damage in abdominal compartment syndrome in the rat [PubMed: 25616531]
The American Journal of Sports Medicine Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo [PubMed: 26362437]
MEDICAL SCIENCES ДИНАМИКА ЦИТОКИНОВОГО ПРОФИЛЯ В ОЦЕНКЕ ДИНАМИКА ЦИТОКИНОВОГО ПРОФИЛЯ В ОЦЕНКЕ ЭФФЕКТИВНОСТИ РАЗНЫХ МЕТОДОВ СТИМУЛЯЦИИ РЕПАРАТИВНОГО ОСТЕОГЕНЕЗА В ЭКСПЕРИМЕНТЕ [Article: N]
Медицина и здравоохранение ДИНАМИКА ЦИТОКИНОВОГО ПРОФИЛЯ В ОЦЕНКЕ ЭФФЕКТИВНОСТИ РАЗНЫХ МЕТОДОВ СТИМУЛЯЦИИ РЕПАРАТИВНОГО ОСТЕОГЕНЕЗА В ЭКСПЕРИМЕНТЕ [Article: N]
Journal of Equine Veterinary Science Synovial Fluid and Serum Concentrations of Interleukin-1 Receptor Antagonist and Interleukin-2 [Science: Article]
Mediators Inflamm Effect of TLR4/MyD88 Signaling Pathway on Expression of IL-1 and TNF-in Synovial Fibroblasts from Temporomandibular Joint Exposed to Lipopolysaccharide [PubMed: 25810567]
J Reprod Immunol The immunomodulating effect of seminal plasma on T cells [PubMed: 25799173]
J Thorac Cardiovasc Surg Annexin V homodimer protects against ischemia reperfusion–induced acute lung injury in lung transplantation [PubMed: 26725713]
J Breath Res Effects of different ventilation strategies on exhaled nitric oxide in geriatric abdominal surgery [PubMed: 25719610]
PLoS One Low Shear Stress Induced HMGB1 Translocation and Release via PECAM-1/PARP-3 Pathway to Induce Inflammation Response [PubMed: 25793986]
Fertil Steril Inflammosome in the human endometrium: further step in the evaluation of the “maternal side” [PubMed: 26474737]
J Biol Chem The Blockade of NF-κB Activation by a Specific Inhibitory Peptide has a Strong Neuroprotective Role in a Sprague-Dawley Rat Kernicterus Model [PubMed: 26499797]
J Vet Sci Autologous processed plasma: cytokine profile and effects upon injection into healthy equine joints. [PubMed: 25269714]
Mol Med Rep Ameliorative effects of Gualou Guizhi decoction on inflammation in focal cerebral ischemic-reperfusion injury [PubMed: 25815894]
J Interferon Cytokine Res Aggregatibacter actinomycetemcomitans Invasion Induces Interleukin-1β Production Through Reactive Oxygen Species and Cathepsin B [PubMed: 25789553]
удк Циток [Cgi-Bin: Irbis_Nbuv]
中华临床医生杂志 中性粒细胞明胶酶相关脂质运载蛋白对腹膜透析相关性腹膜炎疗效监测的意义 [Journal: Fulltext]
ANP Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits [Journal: 60965]
Immunol Res Construction of recombinant Mip-FlaA dominant epitope vaccine against Legionella pneumophila and evaluation of the immunogenicity and protective immunity [PubMed: 26607265]
The Journal of Nutritional Biochemistry Protective role of n6/n3 PUFA supplementation with varying DHA/EPA ratios against atherosclerosis in mice [Pubmed:27142749]
Infaction and Immunity Biological Activities of Uric Acid in Infection Due to Enteropathogenic and Shiga-Toxigenic Escherichia coli [Pubmed:26787720]
Scientific Reports Cellular uptake of exogenous calcineurin B is dependent on TLR4/MD2/CD14 complexes, and CnB is an endogenous ligand of TLR4 [Pubmed:27090571]
Journal of Translational Medicine Modulation of the sympathetic nervous system by renal denervation prevents reduction of aortic distensibility in atherosclerosis prone ApoE-deficient rats [Pubmed:27277003]
Genetics and Molecular Research Effect of ozone on vascular endothelial growth factor (VEGF) and related inflammatory cytokines in rats with diabetic retinopathy [Pubmed:27323014]
Journal of Equine Veterinary Science Interleukin-1 Receptor Antagonist and Interleukin-1 Beta Levels in Equine Synovial Fluid of Normal and Osteoarthritic Joints: Influence of Anatomic Joint Location and Repeated Arthrocentesis [science:S0737080615300757]
Chinese Chemical Letters Screening the anti-gout traditional herbs from TCM using an in vitro method [science:S1001841716301450]
Front Microbiol Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In Vivo [Pubmed:27252695]
PLoS One. Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain [Pubmed:26745377]
Neuroscience The inhibition of transforming growth factor beta-activated kinase 1 contributed to neuroprotection via inflammatory reaction in pilocarpine-induced rats with epilepsy [Pubmed:27012613]
Neuroscience Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E [Pubmed:27235741]
Research in Veterinary Science A chimeric protein composed of the binding domains ofClostridium perfringens phospholipase C and Trueperella pyogenes pyolysin induces partial immunoprotection in a mouse model [Pubmed:27473983]
SpringerPlus Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression ofHMGB1/RAGE/NF-ΚB pathway. [Pubmed:27026909]
The Journal of Thoracic and Cardiovascular Surgery Annexin V homodimer protects against ischemia reperfusion–induced acute lung injury in lung transplantation [Pubmed:26725713]
International Immunopharmacology Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery [Pubmed:26802602]
J Stroke Cerebrovasc Dis. Curcumin Attenuates Inflammation, Oxidative Stress, and Ultrastructural Damage Induced by Spinal Cord Ischemia–Reperfusion Injury in Rats [Pubmed:26935117]
Scientific publications in peer reviewed journals Evidence-based review of efficacy and adverse effects of joint medication and evaluation of synovial fluid and serum markers for osteoarthritis in the horse [receive:101658]
Asian Pacific Journal of Tropical Medicine Perfusion of gastrodin in abdominal aorta for alleviating spinal cord ischemia reperfusion injury [science:S1995764516300955]
Life Sci. Carcinoembryonic antigen related cellular adhesion molecule 1 alleviates dextran sulfate sodium-induced ulcerative colitis in mice [Pubmed:26898127]
Biol Trace Elem Res. Analysis of Ionomic Profiles of Canine Hairs Exposed to Lipopolysaccharide (LPS)-Induced Stress [Pubmed:26758868]
Basic Clin Pharmacol Toxicol Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats [Pubmed:26833867]
Virol J Classical swine fever virus NS5A protein changed inflammatory cytokine secretion in porcine alveolar macrophages by inhibiting the NF-κB signaling pathway [Pubmed:27296632]
Int J Mol Sci. Dexmedetomidine Protects Rat Liver against Ischemia-Reperfusion Injury Partly by the α2A-Adrenoceptor Subtype and the Mechanism Is Associated with the TLR4/NF-κB Pathway [Pubmed:27347929]
Journal of Neuroinflammation Upregulation of neuronal zinc finger protein A20 expression is required for electroacupuncture to attenuate the cerebral inflammatory injury mediated by the nuclear factor-kB signaling pathway in cerebral ischemia/reperfusion rats [pubmed:27716383]
Journal of Agricultural Biotechnology Gln Attenuates LPS-induced Inflammatory Injury of Bos taurus Testis Sustentacular Cells [10610]
Front Pharmacol Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata [pubmed:27803670]
Journal of Equine Veterinary Science Evaluation of Two Protocols Using Autologous Conditioned Serum for Intra-articular Therapy of Equine Osteoarthritis—A Pilot Study Monitoring Cytokines and Cartilage-Specific Biomarkers [S0737080616303720]
immunology letters Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila. [pubmed:28366526]
Lipids in Health and Disease Protective effects of various ratios of DHA/EPA supplementation on high-fat diet-induced liver damage in mice. [pubmed:28356106]
biomedicine & pharmacotherapy Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation. [pubmed:28033582]
International Journal of Molecular Medicine The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats [pubmed:27430552]
Springerplus Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway [pubmed:27026909]
Andrology Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis … [doi:10.1111]
Molecular Immunology Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma [pubmed:27289030]
Cellular Physiology and Biochemistry The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. [pubmed:27576607]
Physiological Research Intravenous dexamethasone attenuated inflammation and influenced apoptosis of lung cells in an experimental model of acute lung injury. [pubmed:28006948]
World Journal of Gastroenterology  Alterations in gut microbiota during remission and recurrence of diabetes after duodenal-jejunal bypass in rats [pubmed:27547013]
Journal of Orthopaedic Surgery and Research  No midterm advantages in the middle term using small intestinal submucosa and human amniotic membrane in Achilles tendon transverse tenotomy [pubmed:27881176]
Molecular Medicine Reports C‑reactive protein/oxidized low density lipoprotein/β2‑glycoprotein i complexes induce lipid accumulation and inflammatory reaction in macrophages via p38/mitogen‑ … [10.3892]
Poultry Science ALV-J strain SCAU-HN06 induces innate immune responses in chicken primary monocyte-derived macrophages [pubmed:27486255]
Molecular Medicine Reports Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects [pubmed:27432278]
International Journal of Molecular Sciences PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2 [pubmed:27973457]
The American Journal of Chinese Medicine Pinellia ternata Attenuates Mucus Secretion and Airway Inflammation after InhaledCorticosteroid Withdrawal in COPD Rats. [pubmed:27430907]
The Journal of Comenius University in Bratislava Effects of Conventional Mechanical Ventilation Performed by Two Neonatal Ventilators on the Lung Functions of Rabbits with Meconium-Induced Acute Lung Injury [acm.2017.16.issue-3]
Journal of Physiology and Pharmacology Effects of budesonide on the lung functions, inflammation and apoptosis in a saline-lavagemodel of acute lung injury. [pubmed:28195073]
Cellular Physiology and Biochemistry MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a andRegulating Renal Tubular Cell Pyroptosis. [pubmed:28006785]
Oncotarget Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation andapoptosis in diabetic cardiomyopathy. [pubmed:27027354]
Life Sciences Bone fracture healing is delayed in splenectomic rats [pubmed:27956350]
Sci Total Environ. The effects of particulate matter on inflammation of respiratory system: Differences betweenmale and female. [pubmed:28174048]
Food Funct. Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through the MAPK and NF-κB pathways. [pubmed:28256654]
PLoS One. Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders. [pubmed:28207788]
Journal of Photochemistry and Photobiology B: Biology Efficacy of scaling and root planning with and without adjunct Nd:YAG laser therapy on clinical periodontal parameters and gingival crevicular fluid interleukin 1-beta and tumor necrosis factor-alpha levels among patients with periodontal disease: A prospective randomized split-mouth clinical study. [pubmed:28282558]
Journal of Cellular Physiology Autophagy maintains the integrity of endothelial barrier in LPS-induced lung injury. [pubmed:28328069]
Biomedicine & pharmacotherapy= Biomedecine & pharmacotherapie Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion [pubmed:28273631]
Journal of Neurochemistry β‐Caryophyllene protects in vitro neurovascular unit against oxygen‐glucose deprivation and re‐oxygenation‐induced injury [pubmed:27565895]
Procalcitonin und proinflammatorische Zytokine in der bronchoalveolären Lavage beim lungenkranken Pferd unter inhalativer Glukokortikoidtherapie [FUDISS_thesis_000000103830]
留言咨询