低氧诱导因子1α(HIF1a)多克隆抗体

Polyclonal Antibody to Hypoxia Inducible Factor 1 Alpha (HIF1a)

HIF1-A; MOP1; PASD8; Basic Helix-Loop-Helix Transcription Factor; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78

  • 低氧诱导因子1α(HIF1a)多克隆抗体 产品包装(模拟)
  • 低氧诱导因子1α(HIF1a)多克隆抗体 产品包装(模拟)
  • 低氧诱导因子1α(HIF1a)多克隆抗体 DAB staining on IHC-P; Samples: Rat Kidney Tissue; Primary Ab: 10µg/ml Rabbit Anti-Rat HIF1a Antibo
  • PAA798Ra01.jpg Figure. Western Blot; Sample: Recombinant HIF1a, Rat.
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对HIF1a的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别HIF1a。

用法

Western blotting: 0.5-2µg/mL;1:180-700
Immunohistochemistry: 5-20µg/mL;1:18-70
Immunocytochemistry: 5-20µg/mL;1:18-70
Optimal working dilutions must be determined by end user.

储存

经常使用则4°C保存。-20°C保存不超过一年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

相关产品

编号 适用物种:Rattus norvegicus (Rat,大鼠) 应用(仅供研究使用,不用于临床诊断!)
RPA798Ra01 低氧诱导因子1α(HIF1a)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA798Ra02 低氧诱导因子1α(HIF1a)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA798Ra01 低氧诱导因子1α(HIF1a)多克隆抗体 WB; IHC; ICC; IP.
PAA798Ra02 低氧诱导因子1α(HIF1a)多克隆抗体 WB; IHC; ICC; IP.
LAA798Ra71 低氧诱导因子1α(HIF1a)多克隆抗体(生物素标记) WB; IHC; ICC.
SEA798Ra 低氧诱导因子1α(HIF1a)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA798Ra 低氧诱导因子1α(HIF1a)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.

参考文献

杂志 参考文献
Cancer Chemotherapy and Pharmacology Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells. [PubMed: 19466611]
European Journal of Pharmacology Baicalin suppresses lung carcinoma and lung metastasis by SOD mimic and HIF-1α inhibition [ScienceDirect: S0014299909011352]
PLoS ONE Lactate Dehydrogenase 5 Expression in Non-Hodgkin Lymphoma Is Associated with the Induced Hypoxia Regulated Protein and Poor Prognosis [PubMed: PMC3781153]
International Journal of Molecular Medicine Selective inhibition of PKCβ2 preserves cardiac function after myocardial infarction and is associated with improved angiogenesis of ischemic myocardium in diabetic rats [Pubmed: 24002353]
Canadian Journal of Physiology and Pharmacology Modulation of arginine and asymmetric dimethylarginine concentrations in liver and plasma by exogenous hydrogen sulfide in LPS-induced endotoxemia [Pubmed: 24289078]
US8569372 B2 Method for preventing or treating a disease, disorder or condition induced by retina ischemia [US8569372]
J Surg Res. Effects of adrenomedullin and vascular endothelial growth factor on ischemia/reperfusion injury in skeletal muscle in rats. [Pubmed: 23816242]
PLoS One. HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis [Plos: Source]
Journal of Physiological Anthropology Telomeres are elongated in rats exposed to moderate altitude [Pubmed:Pmc4088304]
Molecular Medicine Reports Resveratrol abrogates the effects of hypoxia on cell proliferation, invasion and EMT in osteosarcoma cells through downregulation of the HIF-1α protein. [Pubmed:25384583]
International Journal of Pharmaceutics The enhancement of gene silencing efficiency with chitosan-coated liposome formulations of siRNAs targeting HIF-1α and VEGF [Pubmed:25445537]
International Journal of Molecular Medicine Effect of combined treatment with rosuvastatin and protein kinase Cβ2 inhibitor on angiogenesis following myocardial infarction in diabetic rats [Pubmed:25524396]
International Journal of Developmental Neuroscience Maternal omega-3 fatty acid supplementation to a vitamin B 12 deficient diet normalizes angiogenic markers in the pup brain at birth [PubMed: 25889224]
Eur Surg Res Determination of the Preferred Conditions for the Isolated Perfusion of Porcine Kidneys [PubMed: 25341590]
Sci Rep Oxygen-induced cell migration and on-line monitoring biomarkers modulation of cervical cancers on a microfluidic system [PubMed: 25905434]
Evidence-Based Complementary and Alternative Medicine Metabolomic Analysis of Biochemical Changes in the Plasma of High-Fat Diet and Streptozotocin-Induced Diabetic Rats after Treatment with Isoflavones Extract of Radix Puerariae [pmc:PMC4794592]
Biol Trace Elem Res. Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α [Pubmed:27121973]
Раны и раневые инфекции. Использование гипоксического прекондиционирования для подготовки аутодермотрансплантата у больных со скомпрометированной микроциркуляцией [91]
Biological Trace Element Research Roles of Copper in Hepatocarcinogenesis via the Activation of Hypoxia-Inducible Factor-1α. [pubmed:27121973]
Experimental and Therapeutic Medicine Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis [etm:13]
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