M2-型丙酮酸激酶(PKM2)多克隆抗体

Polyclonal Antibody to Pyruvate kinase isozymes M2 (PKM2)

M2PK; PKM; M2-PK; PKM1; CTHBP; OIP3; PK3; PKM; TCB; THBP1; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Cytosolic thyroid hormone-binding protein; Pyruvate Kinase, Muscle

  • M2-型丙酮酸激酶(PKM2)多克隆抗体 产品包装(模拟)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 产品包装(模拟)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P; Samples: Rat Testis Tissue; Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Samples: Rat Intestine Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Samples: Rat Kidney Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Samples: Rat Stomach Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Samples: Rat Spleen Tissue;
    Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Sample: Rat Colon Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Sample: Rat Cerebrum Tissue;
    Primary Ab: 10ug/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Sample: Rat Lymph node Tissue;
    Primary Ab: 10ug/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Sample: Rat Testis Tissue
    Primary Ab: 10µg/ml Rabbit Anti-Rat PKM2 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 DAB staining on IHC-P;
    Sample: Rat Lung Tissue;
    Primary Ab: 10ug/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 FITC staining on IF;
    Samples: Human MCF7 cell;
    Primary Ab: 20μg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 1μg/ml FITC-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb18)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 AF488 staining on IF;
    Sample: Hela cell
    Primary Ab: 20µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 2μg/ml AF488-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb11)
  • PAA588Ra01.jpg WB图
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 Western Blot; Sample: Human HepG2 cell lysate;
    Primary Ab: 2µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 Western Blot; Sample: Human MCF7 cell lysate;
    Primary Ab: 2µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 Western Blot; Sample: Human Hela cell lysate;
    Primary Ab: 2µg/ml Rabbit Anti-Rat PKM2 Antibody
    Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • M2-型丙酮酸激酶(PKM2)多克隆抗体 HepG2 human hepatocellular carcinoma cell line was stained with rabbit Anti-rat PKM2 Polyclonal Antibody (Catalog # PAA588Ra01, filled red histogram) or Isotype control antibody (Catalog # IS067-Rb01, filled green histogram), followed by APC-conjugated Anti-rabbit IgG Secondary Antibody (Catalog # SAA544Rb15). Cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100.
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对PKM2的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别PKM2。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Rattus norvegicus (Rat，大鼠) 应用(仅供研究使用，不用于临床诊断！)
RPA588Ra01 M2-型丙酮酸激酶(PKM2)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA588Ra01 M2-型丙酮酸激酶(PKM2)多克隆抗体 WB; IHC; ICC; IP.
FAA588Ra01 抗M2-型丙酮酸激酶(PKM2)多克隆抗体 Flow cytometry.
MAA588Ra21 M2-型丙酮酸激酶(PKM2)单克隆抗体 WB; IHC; ICC; IP.
SEA588Ra M2-型丙酮酸激酶(PKM2)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA588Ra M2-型丙酮酸激酶(PKM2)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.

参考文献

杂志 参考文献
Cancer Research Antigen Presentation by Dendritic Cells in Tumors Is Disrupted by Altered Metabolism that Involves Pyruvate Kinase M2 and Its Interaction with SOCS3 [AACR: 70189]
Molecular BioSystems Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer [Pubmed:25483567]
Tumour Biol M2 isoform of pyruvate kinase (PKM2) is upregulated in Kazakh’s ESCC and promotes proliferation and migration of ESCC cells [PubMed: 26404132]
Oncotarget Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis [Pubmed:29707118]
Journal of Neurotrauma Acteoside improves muscle atrophy and motor function by inducing new myokine secretion in chronic spinal cord injury [Pubmed: 30318996]
Cell Reports Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway [Pubmed: 32049010]
Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC) []
Cancer Cell International Bufalin Induced Mitochondrial Dysfunction Promotes Apoptosis of Glioma Cells by Regulating Annexin A2 and DRP1 Proteins []
Cancer Cell Int Bufalin induces mitochondrial dysfunction and promotes apoptosis of glioma cells by regulating Annexin A2 and DRP1 protein expression [34376212]
Life (Basel) Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib [34947916]
留言咨询