干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法)

ELISA Kit for Interferon Gamma (IFNg)

IFN-G; IFG; IFI; INFr; IFN, Immune Interferon

  • 干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法) 产品包装(模拟)
  • 干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法) 产品包装(模拟)
  • 干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法) 实验结果图
  • SEA049Hu.jpg 标准曲线图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

本试剂盒用于检测干扰素γ(IFNg)，经检测与其它相似物质无明显交叉反应。
由于受到技术及样本来源的限制，不可能完成对所有相关或相似物质交叉反应检测，因此本试剂盒有可能与未经检测的其它物质有交叉反应。

回收率

分别于定值血清及血浆样本中加入一定量的干扰素γ(IFNg)（加标样品），重复测定并计算其均值，回收率为测定值与理论值的比率。

样本 回收率范围(%) 平均回收率(%)
serum(n=5) 82-90 86
EDTA plasma(n=5) 88-97 94
heparin plasma(n=5) 94-103 99

精密度

精密度用样品测定值的变异系数CV表示。CV(%) = SD/mean×100
批内差：取同批次试剂盒对低、中、高值定值样本进行定量检测,每份样本连续测定20 次，分别计算不同浓度样本的平均值及SD值。
批间差：选取3个不同批次的试剂盒分别对低、中、高值定值样本进行定量测定，每个样本使用同一试剂盒重复测定8次，分别计算不同浓度样本的平均值及SD值。
批内差： CV<10%
批间差： CV<12%

线性

在定值血清及血浆样本内加入适量的干扰素γ(IFNg)，并倍比稀释成1:2，1:4，1:8，1:16的待测样本，线性范围即为稀释后样本中干扰素γ(IFNg)含量的测定值与理论值的比率。

样本 1:2 1:4 1:8 1:16
serum(n=5) 90-101% 92-101% 78-96% 86-101%
EDTA plasma(n=5) 78-94% 89-103% 81-98% 81-93%
heparin plasma(n=5) 85-92% 98-105% 78-103% 85-101%

稳定性

经测定，试剂盒在有效期内按推荐温度保存，其活性降低率小于5%。
为减小外部因素对试剂盒破坏前后检测值的影响，实验室的环境条件需尽量保持一致，尤其是实验室内温度、湿度及温育条件。其次由同一实验员来进行操作可减少人为误差。

实验流程

1. 实验前标准品、试剂及样本的准备；
2. 加样（标准品及样本）100µL，37°C孵育1小时；
3. 吸弃，加检测溶液A100µL，37°C孵育1小时；
4. 洗板3次；
5. 加检测溶液B100µL，37°C孵育30分钟；
6. 洗板5次；
7. 加TMB底物90µL，37°C孵育10-20分钟；
8. 加终止液50µL，立即450nm读数。

实验原理

将干扰素γ(IFNg)抗体包被于96孔微孔板中，制成固相载体，向微孔中分别加入标准品或标本，其中的干扰素γ(IFNg)与连接于固相载体上的抗体结合，然后加入生物素化的干扰素γ(IFNg)抗体，将未结合的生物素化抗体洗净后，加入HRP标记的亲和素，再次彻底洗涤后加入TMB底物显色。TMB在过氧化物酶的催化下转化成蓝色，并在酸的作用下转化成最终的黄色。颜色的深浅和样品中的干扰素γ(IFNg)呈正相关。用酶标仪在450nm波长下测定吸光度(O.D.值)，计算样品浓度。

相关产品

编号 适用物种：Homo sapiens (Human，人) 应用(仅供研究使用，不用于临床诊断！)
UAPA049Hu61 干扰素γ(IFNg)活性蛋白 Cell culture; Activity Assays.
UEPA049Hu61 干扰素γ(IFNg)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
UAPA049Hu01 干扰素γ(IFNg)活性蛋白 Cell culture; Activity Assays.
URPA049Hu01 干扰素γ(IFNg)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
UPAA049Hu01 干扰素γ(IFNg)多克隆抗体 WB; IHC; ICC; IP.
UPAA049Hu06 干扰素γ(IFNg)多克隆抗体 WB; IHC; ICC; IP.
UFAA049Hu01 抗干扰素γ(IFNg)多克隆抗体 Flow cytometry.
ULAA049Hu71 干扰素γ(IFNg)多克隆抗体(生物素标记) WB; IHC; ICC.
ULAA049Hu81 干扰素γ(IFNg)多克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
UMAA049Hu22 干扰素γ(IFNg)单克隆抗体 WB; IHC; ICC; IP.
URAA049Hu21 干扰素γ(IFNg)重组抗体 WB; IF; ICC; IHC; IP; FCM.
UMAA049Hu21 干扰素γ(IFNg)单克隆抗体 WB
UMAA049Hu26 干扰素γ(IFNg)单克隆抗体 WB; IHC; ICC; IP.
UFAA049Hu02 抗干扰素γ(IFNg)单克隆抗体 FCM
ULAA049Hu72 干扰素γ(IFNg)单克隆抗体(生物素标记) WB; IHC; ICC.
ULAA049Hu82 干扰素γ(IFNg)单克隆抗体(异硫氰酸荧光素标记) WB; IHC; ICC; IF.
USEA049Hu 干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
UHEA049Hu 干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法,高敏型) Enzyme-linked immunosorbent assay for Antigen Detection.
UMEA049Hu 干扰素γ(IFNg)检测试剂盒(酶联免疫吸附试验法,小样本) Enzyme-linked immunosorbent assay for Antigen Detection.
UAEA049Hu 抗干扰素γ抗体(Anti-IFNg)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antibody Detection.
USCA049Hu 干扰素γ(IFNg)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
ULMA049Hu 干扰素γ(IFNg)等多因子检测试剂盒(流式荧光发光法) FLIA Kit for Antigen Detection.
UPSA049Hu01 干扰素γ(IFNg)抗体对 ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
UKSA049Hu01 干扰素γ(IFNg)检测试剂盒DIY材料(酶联免疫吸附试验法) Main materials for "Do It (ELISA Kit) Yourself".

参考文献

杂志 参考文献
Vaccine Bacillus Calmette-Guérin vaccination using a microneedle patch [PubMed: 21277407]
Journal of Animal and Veterinary Advances Tryptophan Stimulates Immune Response in Broiler Chickens Challenged with Infectious Bursal Disease Vaccine [Medwell: 2010610616]
Journal of Animal and Veterinary Advances Immunostimulatory Effects of Arginine in Broiler Chickens Challenged with Vaccine Strain of Infectious Bursal Disease Virus [Medwell: 2010594600]
PLoS ONE Vaccination with Recombinant Mycobacterium tuberculosis PknD Attenuates Bacterial Dissemination to the Brain in Guinea Pigs [PubMed: PMC3679071]
Veterinary Research Foot-and-mouth disease virus-like particles produced by a SUMO fusion protein system in?Escherichia coli?induce potent protective immune responses in guinea pigs, swine and cattle [PubMed: PMC3720265]
International Journal of Poultry Science Immune Responses to Eimeria tenella Sporozoite Protein as Vaccine to Broiler Against Coccidiosis [Pjbs: Source]
European Journal of Pharmacology Protective effects of neferine on amiodarone-induced pulmonary fibrosis in mice [Pubmed: 23792144]
Life Sci. Attenuation of renal ischemia/reperfusion injury by a?aí extract preconditioning in a rat model [Pubmed:25476829]
Global Journal of Pharmacology Protective Effect of Minocycline Against Bacterial Infection-Induced Sickness Behavior in Rats [Org:Source]
PLoS One. Development of CpG-Oligodeoxynucleotides for Effective Activation of Rabbit TLR9 Mediated Immune Responses [Pubmed:25269083]
Oncotarget Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils [Pubmed:25347345]
Journal of Surgical Research Exogenous carcinoembryonic antigen-related cell adhesion molecule 1 suppresses 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in mice [Pubmed:25724769]
Genet Mol Res Protective effect and mechanism of probucol in the treatment of spinal cord injury [PubMed: 26214485]
Biomedical Research The toxic effect of nickel nanoparticles on oxidative stress and inflammatory markers. [Articles: ]
Mol Med Rep Roles of lipoxin A4 receptor activation and anti-interleukin-1β antibody on the toll-like receptor 2/mycloid differentiation factor 88/nuclear factor-κB pathway in airway inflammation induced by ovalbumin [PubMed: 25760938]
veterinary research forum Evaluation of proliferation and cytokines production by mitogen-stimulated bovine peripheral blood mononuclear cells [Article_14936_6.Html: ]
Immunologic Research Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE12 and is crucial for liver transplant tolerance [PubMed: 25982596]
Parasitol Res Trypanosoma cruzi infection and benznidazole therapy independently stimulate oxidative status and structural pathological remodeling of the liver tissue in mice [PubMed: 25912691]
International Journal of Immunopathology & Pharmacology Sea buckthorn (Hippophae rhamnoides L.) oil protects against chronic stress-induced inhibitory function of natural killer cells in rats [PubMed: 26684638]
J Reprod Immunol The immunomodulating effect of seminal plasma on T cells [PubMed: 25799173]
Advanced Functional Materials Nanogel‐Incorporated Physical and Chemical Hybrid Gels for Highly Effective Chemo–Protein Combination Therapy [Doi: 10.1002]
Vet Immunol Immunopathol Immune responses of pigs immunized with a recombinant porcine reproductive and respiratory syndrome virus expressing porcine GM-CSF [PubMed: 26300317]
Virol J Rescue and evaluation of a recombinant PRRSV expressing porcine Interleukin-4 [PubMed: 26573719]
J Interferon Cytokine Res Possible Association of IFN-γ Gene [PubMed: 26154533]
Oncotarget Rituximab-induced HMGB1 release is associated with inhibition of STAT3 activity in human diffuse large B-cell lymphoma [PubMed: 26315113]
Immunol Res Construction of recombinant Mip-FlaA dominant epitope vaccine against Legionella pneumophila and evaluation of the immunogenicity and protective immunity [PubMed: 26607265]
Asian J Pharm Clin Res INFLUENCE OF ZINCOVIT DROP (NUTRITIONAL FOOD SUPPLEMENT) ON IMMUNE SYSTEM IN NORMAL AND CYCLOPHOSPHAMIDE INTOXICATED WISTAR RATS [journals:3790]
Life Sci. Carcinoembryonic antigen related cellular adhesion molecule 1 alleviates dextran sulfate sodium-induced ulcerative colitis in mice [Pubmed:26898127]
United States Patent Application HERPES VIRUS VACCINES AND TREATMENTS [y2016:0067330.html]
Front Pharmacol Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata [pubmed:27803670]
BMC Veterinary Research Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis [pubmed:27553600]
BMC Complementary and Alternative Medicine Reno-protective effect and mechanism study of Huang Lian Jie Du Decoction on lupus nephritis MRL/lpr mice [pubmed:27825337]
immunology letters Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila. [pubmed:28366526]
Antiviral research Evaluation of two strains of Marek's disease virus serotype 1 for the development of recombinant vaccines against very virulent infectious bursal disease virus. [pubmed:27908832]
Vaccine. Efficacy of an autophagy-targeted DNA vaccine against avian leukosis virus subgroup J. [pubmed:28049588]
immunology letters Gemcitabine treatment enhanced the anti-tumor effect of cytokine induced killer cells by depletion of CD4+CD25bri regulatory T cells. [pubmed:27867030]
Taylor & Francis Influences of Hyriopsis cumingii polysaccharides on mice immunosignaling molecules and T lymphocyte differentiation [09540105.2017.1306494]
American Journal of Translational Research Anti-inflammatory effects of Boletus edulis polysaccharide on asthma pathology [pubmed:27830033]
Molecular Immunology Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma [pubmed:27289030]
Basrah Journal of Veterinary Research EVALUATION OF HUMORAL AND CELLULAR IMMUNE RESPONSES TO EIMERIA TENELLA OOCYST PROTEIN AS VACCINE TO BROILER [363-379.pdf]
Journal of Physiology and Pharmacology Effects of budesonide on the lung functions, inflammation and apoptosis in a saline-lavagemodel of acute lung injury. [pubmed:28195073]
Journal of animal physiology and animal nutrition Effects of dietary mixture of garlic (Allium sativum), coriander (Coriandrum sativum) andprobiotics on immune responses and caecal counts in young laying hens. [pubmed:27678135]
Parasitology. Nonsteroidal anti-inflammatory is more effective than anti-oxidant therapy in counteracting oxidative/nitrosative stress and heart disease in T. cruzi-infected mice. [pubmed:28134069]
Vet Immunol Immunopathol.  Porcine GPX1 enhances GP5-based DNA vaccination against porcine reproductive and respiratory syndrome virus. [pubmed:28063474]
Sci Rep.  Long-term use of ceftriaxone sodium induced changes in gut microbiota and immune system. [pubmed:28220870]
Sci Rep.  Assessment of the efficacy of two novel DNA vaccine formulations against highly pathogenic Porcine Reproductive and Respiratory Syndrome Virus. [pubmed:28157199]
Acta Vet Hung. Imbalance of intestinal immune function in piglets infected by porcine circovirus type 2 during the fetal period. [pubmed:28244338]
Gut Pathog. Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice [pubmed:28250847]
Journal of Agricultural and Food Chemistry Effect of boron on thymic cytokine expression, hormone secretion, antioxidant functions, cell proliferation, and apoptosis potential via the ERK1/2 signaling pathway [pubmed:29032684]
Vaccine Poly (d, l-lactide-co-glycolide) nanoparticle-entrapped vaccine induces a protective immune response against porcine epidemic diarrhea virus infection in piglets [pubmed:29102169]
Bulgarian Journal of Veterinary Medicine COMPARATIVE EFFICACY OF TWO HETEROLOGOUS CAPRIPOX VACCINES TO CONTROL LUMPY SKIN DISEASE IN CATTLE [ISSN 1311-1477]
Research in Veterinary Science The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs [pubmed:28549299]
Scientific Report Anti-asthmatic efect of pitavastatin through aerosol inhalation is associated with CD4+ CD25+ Foxp3+ T cells in an asthma mouse model [pubmed:28729731]
Austral journal of veterinary sciences The effects of Spirulina platensis (Arthrospira platensis) and Saccharomyces cerevisiae on the distribution and cytokine production of CD4+ and CD8+ T … [S0719-81322017000300185]
18 Evaluation of Cell-mediated Immune Response in PBMCs of Calves Vaccinated by Capri Pox Vaccines Using ELISA and Real-time RT-PCR [DOI: 10.18869/acadpub.rmm.5.2.3]
Scientific Report Stress Induced Polarization of Immune-Neuroendocrine Phenotypes in Gallus gallus [pubmed:28808318]
Pesquisa Veterinária Brasileira Efeito protetor do β-glucano e glutamina em lesões intestinais e imunológicas induzidas por ciratabina (Ara-C) em camundongos [10.159:s0100-736x2017000900013]
Asian Pacific Society of Respirology Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice [pubmed:28122397]
PLOS Neglected Tropical Diseases An attenuated Shigella mutant lacking the RNA-binding protein Hfq provides cross-protection against Shigella strains of broad serotype [pubmed:28727722]
Oncotarget Combination epidermal growth factor receptor variant III peptide-pulsed dendritic cell vaccine with miR-326 results in enhanced killing on EGFRvIII-positive cells [10.18632/oncotarget.15445]
Veterinary Microbiology A bacterial ghost improves the immunological efficacy of a Newcastle disease virus inactivated vaccine [pubmed:28619143]
Canadian Journal of Gastroenterology and Hepatology EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-ݜ傠Signaling Pathway in Rats [10.1155/2017/3057268]
Acta Pharmacologica Sinica Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ. [pubmed:28649126]
Canadian Journal of Gastroenterology and Hepatology EGCG Maintains Th1/Th2 Balance and Mitigates Ulcerative Colitis Induced by Dextran Sulfate Sodium through TLR4/MyD88/NF-κB Signaling Pathway in Rats [10.1155/2017/3057268]
Biomedical Research Associations among interleukin-17, interferon-gamma, and acute coronary syndrome [ISSN 0970-938X]
Molecular Pharmaceutics Double-Edged Effect of Hydroxychloroquine on Human Umbilical Cord-Derived Mesenchymal Stem Cells Treating Lupus Nephritis in MRL/lpr Mice [Pubmed:29668284]
Cancer Science Sonodynamic therapy‐assisted immunotherapy: A novel modality for cancer treatment [Pubmed:29575297]
Prostate Identification and preliminary study of immunogens involved in autoimmune prostatitis in human males [Pubmed:29947032]
Vaccine Immunogenicity and protective efficacy of recombinant fiber-2 protein in protecting SPF chickens against fowl adenovirus 4 [Pubmed:29395523]
Oncology Reports Silencing of Girdin suppresses the malignant behavior of colorectal carcinoma cells [Pubmed:29989653]
Biomed Research International Epstein Barr Virus Infection Affects Function of Cytotoxic T Lymphocytes in Patients with Severe Aplastic Anemia [Pubmed:29862282]
Probiotics Antimicrob Proteins Effect of Multi-Microbial Probiotic Formulation Bokashi on Pro-and Anti-Inflammatory Cytokines Profile in the Serum, Colostrum and Milk of Sows, and in a … [Pubmed:29305686]
Archives of Virology Genetic and immunogenicity analysis of porcine circovirus type 2 strains isolated in central China [Pubmed:29305646]
Food & Nutrition Research Immunomodulatory activity of Lactobacillus plantarum KLDS1. 0318 in cyclophosphamide-treated mice [Pubmed:30026678]
Medical Science Monitor Involvement of T-Helper 9 Activation in a Mouse Model of Allergic Rhinitis [Pubmed:29982264]
Biochemistry (Moscow) Proinflammatory Cytokine Production by CD-1 Mice in Response to Equipotential Doses of PG and  … [10.1134:S0006297918070088]
Oncology Letters Antitumor efficacy of the Runx2‑dendritic cell vaccine in triple‑negative breast cancer in vitro [Pubmed:30127867]
Chinese medical journal Increased Macroautophagy in Interferon-Gamma-Producing T Cells from Patients with Newly Diagnosed Systemic Lupus Erythematosus [Pubmed:29941705]
Journal of Integrative Agriculture Construction of Pullorum ghost by co-expression of lysis gene E and the antimicrobial peptide SMAP29 and evaluation of its immune efficacy in specific … [10.1016:S2095-3119(17)61696-4]
Journal of International Medical Research Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary disease [Pubmed:29950127]
Tropical Animal Health andProduction Effect of reproductive disorders on productivity and reproductive efficiency of dromedary she-camels in relation to cytokine concentration [Pubmed:29423707]
Iranian Journal of Veterinary Science and Technology Immune response characteristics of Capri pox virus vaccines following emergency vaccination of cattle against lumpy skin disease virus [65381]
HUVEC 疫苗联合化疗抗EMT-6 乳腺癌转移实验研究 [Immune99:Source]
خصوصیات پاسخ‌های ایمنی القاء شده ناشی از واکسن زنده تخفیف حدت یافته آبله بزی سویه گرگان بر علیه بیماری لمپی اسکین در گاو‎ []
Cancer Biomarkers Soluble LAG3 acts as a potential prognostic marker of gastric cancer and its positive correlation with CD8+ T cell frequency and secretion of IL-12 and INF-γ in … [Pubmed: 30223387]
Veterinary Microbiology PD-1 blockade inhibits lymphocyte apoptosis and restores proliferation and anti-viral immune functions of lymphocyte after CP and NCP BVDV infection in vitro [Doi: 10.1016/j.vetmic.2018.10.014]
Cellular Immunology NK Cells Suppress CD8+ T Cell Immunity via NKG2D in Severe Aplastic Anemia [Doi: 10.1016/j.cellimm.2018.10.004]
Immunology DNA prime‐protein boost vaccine encoding HLA‐A2,‐A24 and‐DR 1 restricted epitopes of Ca NA 2 against visceral leishmaniasis []
Medical Mycology Intradermal injection of Pythium insidiosum protein antigens for improved diagnosis and treatment of pythiosis in an experimental model [Pubmed: 30260397]
Bioscience, Biotechnology, and Biochemistry In vitro and in vivo cancer cell apoptosis triggered by competitive binding of Cinchona alkaloids to the RING domain of TRAF6 []
BBA- Molecular Basis of Disease Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic … [Pubmed: 30553018]
Journal of Veterinary Research Early cytokine response after vaccination with Coxiella burnetii phase I in an infected herd of dairy cattle []
Journal of Neuroinflammation Amlexanox attenuates experimental autoimmune encephalomyelitis by inhibiting dendritic cell maturation and reprogramming effector and regulatory T cell … [Pubmed: 30823934]
Viruses Construction and Immunogenicity of Novel Chimeric Virus-Like Particles Bearing Antigens of Infectious Bronchitis Virus and Newcastle Disease Virus [Pubmed: 30871190]
American Journal of Physiology-Endocrinology and Metabolism Hyperandrogenism and insulin resistance induce gravid uterine defects in association with mitochondrial dysfunction and aberrant ROS production [Pubmed: 30860876]
American Journal of Pathology Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in 3xTg-AD Mice [Pubmed: 30980800]
Frontiers in Microbiology Local probiotic Lactobacillus crispatus and Lactobacillus delbrueckii exhibit strong antifungal effects against vulvovaginal candidiasis in a rat model []
bulletin of experimental biology and medicine Quantitative and Qualitative Characterization of Phagocytic Activity of Macrophages of Bone Marrow and Fetal Origin [Pubmed: 31183654]
Viruses Co-Expression of Chicken IL-2 and IL-7 Enhances the Immunogenicity and Protective Efficacy of a VP2-Expressing DNA Vaccine against IBDV in Chickens [Pubmed: 31137731]
Biomaterials Magnetic-responsive and targeted cancer nanotheranostics by PA/MR bimodal imaging-guided photothermally triggered immunotherapy []
Chemosphere Atmospheric H2S triggers immune damage by activating the TLR-7/MyD88/NF-κB pathway and NLRP3 inflammasome in broiler thymus []
Health and Medicine Antiallergical Effect of New Combined Nazal Aerodisperse System in the Conditions of Experimental Allergic Rhinitis []
Free Radical Biology and Medicine Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat [Pubmed: 31255668]
Animals Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training [Pubmed: 31462005]
Infection and Drug Resistance Disseminated And Infection Accompanied Sweet's Syndrome In A Patient With Anti-Interferon-γ Autoantibodies: A Case Report. [Pubmed: 31632104]
Open Forum Infectious Diseases Characterization of Anti–Interferon-γ Antibodies in HIV-Negative Patients Infected With Disseminated and Cryptococcosis. [Pubmed: 31660325]
Polish Journal of Veterinary Sciences Effect of postpartum administration of ketoprofen on proinflammatory cytokine concentration and their correlation with lipogenesis and ketogenesis in Holstein … [Pubmed: 31560476]
Experimental Cell Research CD4+ CD25+ Tregs as dependent factor in the course of bleomycin-induced pulmonary fibrosis in mice [Pubmed: 31678213]
International Immunopharmacology Melatonin alleviates oxidative stress in sleep deprived mice: Involvement of small intestinal mucosa injury [Pubmed: 31835081]
International Journal of Rheumatic Diseases Effects of thalidomide on Th17, Treg cells and TGF‐β1/Smad3 pathway in a mouse model of systemic sclerosis [Pubmed: 31840939]
Frontiers in Immunology The Increase in IL-1β in the Early Stage of Heatstroke Might Be Caused by Splenic Lymphocyte Pyroptosis Induced by mtROS-Mediated Activation of the … [Pubmed: 31921131]
Nutrients Rotundic Acid Protects against Metabolic Disturbance and Improves Gut Microbiota in Type 2 Diabetes Rats [Pubmed: 31887996]
Transboundary and Emerging Diseases Pathogenicity of porcine reproductive and respiratory syndrome virus (ORF5 RFLP 1–7–4 viruses) in China [Pubmed: 32187856]
Nanomedicine The toxicity of alumina nanoparticles to immune system in mice [Pubmed: 32162999]
Scientific Reports Serum sHLA-G: Significant diagnostic biomarker with respect to therapy and immunosuppressive mediators in Head and Neck Squamous Cell Carcinoma [Pubmed: 32123232]
American Journal of Translational Research Inhibitory effects of catalpol coordinated with budesonide and their relationship with cytokines and Interleukin-13 expression [Pubmed: 31737193]
Journal of Inflammation Research Active Cousinia thomsonii Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NFκB Cascade in Lipopolysaccharide-Induced … [Pubmed: 33173324]
Toxicol Appl Pharmacol Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling [Pubmed: 33171191]
MOLECULAR AND CELLULAR BIOCHEMISTRY Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMT [Pubmed: 33083950]
BIOMEDICINE & PHARMACOTHERAPY Chlorogenic acid prevents acute myocardial infarction in rats by reducing inflammatory damage and oxidative stress [Pubmed: 33022535]
DRUG AND CHEMICAL TOXICOLOGY Toxicological impact of sodium benzoate on inflammatory cytokines, oxidative stress and biochemical markers in male Wistar rats [Pubmed: 33003960]
Life Sci PIGU promotes hepatocellular carcinoma progression through activating NF-κB pathway and increasing immune escape [Pubmed: 32971102]
Vet Res Construction of polycistronic baculovirus surface display vectors to express the PCV2 Cap (d41) protein and analysis of its immunogenicity in mice and swine [Pubmed: 32907618]
Int Immunopharmacol BNIP3 deletion ameliorated enterovirus 71 infection-induced hand, foot and mouth disease via inhibiting apoptosis, autophagy, and inflammation in mice [Pubmed: 32717566]
EXPERIMENTAL DERMATOLOGY Decreased suppression of CD8+ and CD4+ T cells by peripheral Regulatory T cells in Generalized Vitiligo due to reduced NFATC1 and FOXP3 proteins [Pubmed: 32682346]
Parasites & Vectors Fasciola gigantica excretory-secretory products (FgESPs) modulate the differentiation and immune functions of buffalo dendritic cells through a mechanism … [Pubmed: 32680553]
Life Sci Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study [Pubmed: 32652140]
cancer immunology immunotherapy TIM-3 blockade combined with bispecific antibody MT110 enhances the anti-tumor effect of γδ T cells [Pubmed: 32588076]
BIOLOGICAL TRACE ELEMENT RESEARCH Association Between Serum Selenium Level and Subclinical Mastitis in Dairy Cattle [Pubmed: 32583225]
Molecular Medicine Reports Aquaporin‑4 deletion ameliorates enterovirus 71 infection in mice [Pubmed: 32582978]
BIOTECHNOLOGY LETTERS Recombinant ferritin nanoparticles can induce dendritic cell maturation through TLR4/NF-κB pathway [Pubmed: 32567013]
Int Immunopharmacol Celastrol attenuates collagen-induced arthritis via inhibiting oxidative stress in rats [Pubmed: 32402948]
Evaluation of lipopolysaccharide-induced acute lung injury attenuation in mice by Glycyrrhiza glabra []
Journal of Functional Foods Polyphenolic extracts from Wushan tea leaves attenuate hepatic injury in CCl4-treated mice []
Indian Journal of Animal Research Immunological Effects of a Single Dose of PLGA Nanoparticles Encapsulated Peptide in Broilers in Comparison to Traditional Vaccines against Infectious Bursal … []
Hormonal and Cytokine Blood Profile of Dairy Cows in the Early Gestation Period []
Experimental autoimmune encephalomyelitis inhibited by Huangqi Guizhi Wuwu Decoction by enhancing Th2 cytokine []
Scientific Reports Immunogenicity and protective efficacy of enterotoxigenic Escherichia coli (ETEC) total RNA against ETEC challenge in a mouse model [33239756]
Animal Effect of alfalfa hay and starter feed supplementation on caecal microbiota and fermentation, growth, and health of yak calves [33610512]
Eur Rev Med Pharmacol Sci Salivary Irisin: potential inflammatory biomarker in recurrent apthous stomatitis patients [33755963]
Biomed Pharmacother Macro- and microtranscriptomic evidence of the monocyte recruitment to regenerating liver after partial hepatectomy in mouse model [33765583]
PLoS One Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment¡ªIn vivo studies [33999928]
Life Sciences p-Coumaric acid ameliorates ionizing radiation-induced intestinal injury through modulation of oxidative stress and pyroptosis [33915129]
Infect Drug Resist Talaromyces marneffei and Burkholderia cepacia Co-Infection in a HIV-Uninfected Patient with Anti-Interferon-¦Ã Autoantibodies [34140785]
Vaccines Construction and Immunogenicity Comparison of Three Virus-Like Particles Carrying Different Combinations of Structural Proteins of Avian Coronavirus Infectious?¡­ [33670249]
Pharmaceutics PK/PD Modeling of the PDE7 Inhibitor¡ªGRMS-55 in a Mouse Model of Autoimmune Hepatitis. Pharmaceutics 2021, 13, 597 [33919375]
Melatonin-mediated MT2 attenuates colitis induced by dextran sodium sulfate via PI3K/AKT/Nrf2/SIRT1/ROR¦Á/NF-¦ÊB signaling pathways [34162146]
How Does the Th1/Th2 Polarization in Milk Change According to the Types of Bacteria that Cause Subclinical Mastitis in Cows? []
Amplified Antitumor Efficacy By A Targeted Drugs Retention and Chemosensitization Strategies-Based ¡°Combo¡± Nanoagent Together With PD-L1 Blockade In?¡­ []
World J Tradit Chin Med Experimental autoimmune encephalomyelitis inhibited by Huangqi Guizhi Wuwu Decoction via Th2 cytokine enhancement []
Cancer Lett Photodynamic therapy induces human esophageal carcinoma cell pyroptosis by targeting the PKM2/caspase-8/caspase-3/GSDME axis [34256094]
J Pharm Pharmacol Alamandine protects against renal ischaemia–reperfusion injury in rats via inhibiting oxidative stress [34244746]
J Nanobiotechnology Amplified antitumor efficacy by a targeted drug retention and chemosensitization strategy-based “combo” nanoagent together with PD-L1 blockade in … [34225744]
Neoplasia PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1 [34325342]
Sci Rep Talaromyces marneffei and nontuberculous mycobacteria co-infection in HIV-negative patients [34376749]
Am J Transl Res Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma [34377237]
J Immunol Res Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus [34395633]
Sci Rep Novel interferon-sensitive genes unveiled by correlation-driven gene selection and systems biology [34508139]
Transl Psychiatry Associations between expression of indoleamine 2, 3-dioxygenase enzyme and inflammatory cytokines in patients with first-episode drug-naive … [34802039]
Infect Drug Resist Retrospective Analysis of 10 Cases of Disseminated Nontuberculous Mycobacterial Disease with Osteolytic Lesions [34785914]
Environmental Research In-vitro oxidative potential and inflammatory response of ambient PM2. 5 in a rural region of Northwest China: Association with chemical compositions and … [34863982]
Eur J Pharm Sci Preclinical study of methotrexate-based hydrogels versus surfactant based liquid crystal systems on psoriasis treatment [34314841]
J Inflamm Res Clenbuterol, a Selective β2-Adrenergic Receptor Agonist, Inhibits or Limits Post-Stroke Pneumonia, but Increases Infarct Volume in MCAO Mice [Pubmed:35058704]
Poult Sci Salmonella phage CKT1 significantly relieves the body weight loss of chicks by normalizing the abnormal intestinal microbiome caused by hypervirulent … [Pubmed:35063807]
ACS Appl Mater Interfaces Combinational Chemoimmunotherapy for Breast Cancer by Codelivery of Doxorubicin and PD-L1 siRNA Using a PAMAM-Incorporated Liposomal Nanoplatform [Pubmed:35138103]
Theranostics Combating multidrug resistance and metastasis of breast cancer by endoplasmic reticulum stress and cell-nucleus penetration enhanced … [Pubmed:35401832]
Inflammopharmacology Silymarin constrains diacetyl-prompted oxidative stress and neuroinflammation in rats: involvements of Dyn/GDNF and MAPK signaling pathway [Pubmed:35366745]
Journal of Nanobiotechnology Biomimetic GBM-targeted drug delivery system boosting ferroptosis for immunotherapy of orthotopic drug-resistant GBM [Pubmed:35351131]
Infection and Drug Resistance Sweet's Syndrome Accompanied by Coinfection with Multiple Pathogens and Disseminated Mycobacterium phlei Infection Presenting with Osteolytic … [Pubmed:35592103]
Sci Rep Clinical findings and predictive factors for positive anti-interferon-γ autoantibodies in patients suffering from a non-tuberculosis mycobacteria or Talaromyces … [Pubmed:35641599]
Biomedicines Deletion of Toxoplasma Rhoptry Protein 38 (PruΔrop38) as a Vaccine Candidate for Toxoplasmosis in a Murine Model [Pubmed:35740356]
Viruses Synergistic Pathogenicity by Coinfection and Sequential Infection with NADC30-like PRRSV and PCV2 in Post-Weaned Pigs [Pubmed:35215787]
Antioxidants Blue Light Alters the Composition of the Jejunal Microbiota and Promotes the Development of the Small Intestine by Reducing Oxidative Stress [Pubmed:35204158]
Oxidative Medicine and Cellular Longevity The Role of Aeromonas-Goblet Cell Interactions in Melatonin-Mediated Improvements in Sleep Deprivation-Induced Colitis [Pubmed:35355860]
Journal of Integrative Medicine Salvadora persica extract attenuates cyclophosphamide-induced hepatorenal damage by modulating oxidative stress, inflammation and apoptosis in rats [Pubmed:35643766]
researchsquare MSC-EVs: A Promising Modulator for Immune Response in Systemic Lupus Erythematosus []
Mljekarstvo Th1/Th2 cytokine polarization in milk according to different pathogens causing subclinical mastitis in cows []
留言咨询