骨钙素(OC)检测试剂盒(酶联免疫吸附试验法)

ELISA Kit for Osteocalcin (OC)

BGLAP; OT; BGP; Bone Gla Protein; Bone Gamma-Carboxyglutamate Protein; Gamma-carboxyglutamic acid-containing protein

  • 骨钙素(OC)检测试剂盒(酶联免疫吸附试验法) 产品包装(模拟)
  • 骨钙素(OC)检测试剂盒(酶联免疫吸附试验法) 产品包装(模拟)
  • 骨钙素(OC)检测试剂盒(酶联免疫吸附试验法) 实验结果图
  • SEA471Ov.jpg 标准曲线图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

本试剂盒用于检测骨钙素(OC)，经检测与其它相似物质无明显交叉反应。
由于受到技术及样本来源的限制，不可能完成对所有相关或相似物质交叉反应检测，因此本试剂盒有可能与未经检测的其它物质有交叉反应。

回收率

分别于定值血清及血浆样本中加入一定量的骨钙素(OC)（加标样品），重复测定并计算其均值，回收率为测定值与理论值的比率。

样本 回收率范围(%) 平均回收率(%)
serum(n=5) 93-101 97
EDTA plasma(n=5) 91-99 95
heparin plasma(n=5) 83-101 94

精密度

精密度用样品测定值的变异系数CV表示。CV(%) = SD/mean×100
批内差：取同批次试剂盒对低、中、高值定值样本进行定量检测,每份样本连续测定20 次，分别计算不同浓度样本的平均值及SD值。
批间差：选取3个不同批次的试剂盒分别对低、中、高值定值样本进行定量测定，每个样本使用同一试剂盒重复测定8次，分别计算不同浓度样本的平均值及SD值。
批内差： CV<10%
批间差： CV<12%

线性

在定值血清及血浆样本内加入适量的骨钙素(OC)，并倍比稀释成1:2，1:4，1:8，1:16的待测样本，线性范围即为稀释后样本中骨钙素(OC)含量的测定值与理论值的比率。

样本 1:2 1:4 1:8 1:16
serum(n=5) 99-105% 95-103% 89-97% 78-95%
EDTA plasma(n=5) 96-104% 96-105% 96-105% 98-105%
heparin plasma(n=5) 82-90% 79-104% 92-102% 82-104%

稳定性

经测定，试剂盒在有效期内按推荐温度保存，其活性降低率小于5%。
为减小外部因素对试剂盒破坏前后检测值的影响，实验室的环境条件需尽量保持一致，尤其是实验室内温度、湿度及温育条件。其次由同一实验员来进行操作可减少人为误差。

实验流程

1. 实验前标准品、试剂及样本的准备；
2. 加样（标准品及样本）100µL，37°C孵育1小时；
3. 吸弃，加检测溶液A100µL，37°C孵育1小时；
4. 洗板3次；
5. 加检测溶液B100µL，37°C孵育30分钟；
6. 洗板5次；
7. 加TMB底物90µL，37°C孵育10-20分钟；
8. 加终止液50µL，立即450nm读数。

实验原理

将骨钙素(OC)抗体包被于96孔微孔板中，制成固相载体，向微孔中分别加入标准品或标本，其中的骨钙素(OC)与连接于固相载体上的抗体结合，然后加入生物素化的骨钙素(OC)抗体，将未结合的生物素化抗体洗净后，加入HRP标记的亲和素，再次彻底洗涤后加入TMB底物显色。TMB在过氧化物酶的催化下转化成蓝色，并在酸的作用下转化成最终的黄色。颜色的深浅和样品中的骨钙素(OC)呈正相关。用酶标仪在450nm波长下测定吸光度(O.D.值)，计算样品浓度。

相关产品

编号 适用物种：Ovis aries; Ovine (Sheep，绵羊) 应用(仅供研究使用，不用于临床诊断！)
SEA471Ov 骨钙素(OC)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.

参考文献

杂志 参考文献
Acta Biomaterialia Surface engineering of titanium with potassium hydroxide and its effects on the growth behavior of mesenchymal stem cells [PubMed: 19963080]
Annals of RSCB Biochemical study of the influence of ad type biophytomodulators in healing of bone defects in rats. [Analelesnbc: source]
Asian-Australasian Association of Animal Societies Variability of Osteocalcin Status in Chinese Holstein Cattle: Do Phylogeny, Vitamin D or Gene Polymorphisms Matter? [Ajas: source]
Nutrition Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity [ScienceDirect: S0899900709004717]
Experimental Biology and Medicine Osteogenic activity of silymarin through enhancement of alkaline phosphatase and osteocalcin in osteoblasts and tibia-fractured mice [Rsm: source]
Archives of Oral Biology Oxytocin promotes bone formation during the alveolar healing process in old acyclic female rats [ScienceDirect: S0003996912001021]
22 Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces [ScienceDirect: S0142961212000865]
Life Sciences Exendin-4 Increases Bone Mineral Density in Type 2 Diabetic OLETF Rats Potentially Through the Down-Regulation of SOST/Sclerostin in Osteocytes [PubMed: 23357248]
Romanian Journal of Morphology and Embryology Serum changes induced by intramedullar experimental administration of bisphosphonates [PubMed: 21424089]
International Journal of Cardiology Valvular osteoclasts in calcification and aortic valve stenosis severity [PubMed: 23452891]
Journal of Physiology and Pharmacology Postnatal administration of 2-oxoglutaric acid improves articular and growth plate cartilages and bone tissue morphology in pigs prenatally treated with dexamethasone [PubMed: 23211309]
Journal of Applied Toxicology Chronic exposure to low concentrations of strontium 90 affects bone physiology but not the hematopoietic system in mice [Wiley: Source]
Chinese Medicine Puerarin promotes osteogenesis and inhibits adipogenesis in vitro [PubMed: PMC3765709]
Nephrology Dialysis Transplantation Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells [PubMed: PMC3611891]
J Anim Physiol Anim Nutr (Berl). Morphological changes of the cartilage and bone in newborn piglets evoked by experimentally induced glucocorticoid excess during pregnancy [Pubmed: 22716040]
Journal of Cranio-Maxillofacial Surgery The use of Tri-Calcium Phosphate (TCP) and stem cells for the regeneration of osteoperiosteal critical-size mandibular bony defects, an in vitro and preclinical study [Pubmed: 24485270]
Nutr Hosp. Effect of the “protein diet” and bone tissue. [Pubmed: 24483972]
International Journal of Cardiology Valvular osteoclasts in calcification and aortic valve stenosis severity. [Pubmed: 23452891]
Food Science & Nutrition Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7 [Onlinelibrary: fsn3.109]
Nutricion Hospitalaria Effect of the “protein diet” and bone tissue [Aulamedica: Source]
Tissue Eng Part A. Toward the Development and Characterization of an Easy Handling Sheet-Like Biohybrid Bone Substitute [Pubmed:25761235]
Basic &amp; Clinical Pharmacology &amp; Toxicology Treatment with Carnitine Enhances Bone Fracture Healing under Osteoporotic and/or Inflammatory Conditions [Wiley:Source]
Food Sci Nutr. Effects and mechanisms of 8‐prenylnaringenin on osteoblast MC3T3‐E1 and osteoclast‐like cells RAW264. 7 [Pubmed:Pmc4221832]
Journal of Cranio-Maxillofacial Surgery The use of TriCalcium Phosphate (TCP) and stem cells for the regeneration of osteoperiosteal critical-size mandibular bony defects, an in vitro and preclinical study [Pubmed:24485270]
Naunyn-Schmiedeberg&#039;s Archives of Pharmacology Treatment with α-lipoic acid enhances the bone healing after femoral fracture model of rats [Pubmed:25038619]
FEBS Letters Low-intensity pulsed ultrasound-induced ATP increases bone formation via the P2X7 receptor in osteoblast-like MC3T3-E1 cells [Pubmed:25542352]
American Diabetes Association Pathophysiological mechanism of bone loss in type 2 diabetes involves inverse regulation of osteoblast function by PPARγ coactivator-1α and skeletal muscle atrogenes: adiponectin receptor 1 as a potential target for reversing diabetes-induced osteopenia [Pubmed:25633418]
International Journal of Nanomedicine Immobilizing osteogenic growth peptide with and without fibronectin on a titanium surface: effects of loading methods on mesenchymal stem cell differentiation [Pubmed:25678785]
Medical Journal fo the Islamic Republic of Iran Transplantation of mesenchymal stem cells, recombinant human BMP-2,and their combination in accelerating the union after osteotomy and increasing, the mechanical strength of extracorporeally irradiated femoral autograft in rat models [Pubmed:25679008]
BioMed Research International Inhibition of osteoclast activation by phloretin through disturbing αvβ3 integrin-c-Src pathway [Pubmed:25834823]
Advances in Medical Sciences The influence of bexarotene, a selective agonist of the retinoid receptor X (RXR), and tazarotene, a selective agonist of the retinoid acid receptor (RAR), on bone metabolism in rats [PubMed: 26569440]
journal of hard Tissue Biology Biological Evaluation of a Prototype Material made of Polyglycolic Acid and Hydroxyapatite [Article: Jhtb]
Bioscience Trends Products of dentin matrix protein-1 degradation by interleukin-1β-induced matrix metalloproteinase-3 promote proliferation of odontoblastic cells [PubMed: 26355224]
J Nutr Biochem Body fat loss induced by calcium in co-supplementation with conjugated linoleic acid is associated with increased expression of bone formation genes in adult mice [PubMed: 26454511]
Int J Mol Med Curcumin alleviates glucocorticoid-induced osteoporosis through the regulation of the Wnt signaling pathway [PubMed: 26677102]
Experimental And Therapeutic Medicine Antiosteoporotic effect of icariin in ovariectomized rats is mediated via the Wnt/β-catenin pathway [Pubmed:27347050]
International Journal of Life Sciences Research Impact of Curcumin and Flaxseed Oil on Bone Turnover in Glucocorticoid-Injected Female Rats [profile:303311214]
Journal of Alloys and Compounds Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants [science:S0045653516302016]
Bone The effects of strength training and raloxifene on bone health in aging ovariectomized rats [Pubmed:26812611]
Biological Trace Element Research Effect of Sodium Fluoride on Bone Biomechanical and Histomorphometric Parameters and on Insulin Signalingand Insulin Sensitivity in Ovariectomized Rats. [Pubmed:26876375]
ANNALS OF ANIMAL SCIENCE Comparison of the effect of a standard inclusion level of inorganic zinc to organic form at lowered level on bone development in growing male Ross broiler chickens [journalprintahead:87]
Annals of Animal Science Comparison of the Effect of a Standard Inclusion Level of Inorganic Zinc to Organic Form at Lowered Level on Bone Development in Growing Male Ross Broiler Chickens [view:87]
J Bone Miner Metab MiR-142-5p promotes bone repair by maintaining osteoblast activity [Pubmed:27085967]
Protective Effect of Soybean and Mushroom against Glucocorticoid-Induced Osteoporosis in Female Rats [:]
Journal of Functional Foods Comparative effects of brown and golden flaxseeds on body composition, inflammation and bone remodelling biomarkers in perimenopausal overweight women [S1756464617301561]
international journal of molecular sciences Evidence of the Role of R-Spondin 1 and Its Receptor Lgr4 in the Transmission of Mechanical Stimuli to Biological Signals for Bone Formation. [pubmed:28272338]
Applied Surface Science The controlled release of simvastatin from TiO2 nanotubes to promote osteoblast differentiation and inhibit osteoclast resorption [S0169433216326861]
Nutrition. Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats. [pubmed:27908549]
Chemico-Biological Interactions Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway [pubmed:27387537]
Biomedicine & Pharmacotherapy Fast and long acting neoflavonoids dalbergin isolated from Dalbergia sissoo heartwood is osteoprotective in ovariectomized model of osteoporosis: Osteoprotective … [S0753332216308484]
Experimental and Therapeutic Medicine Serum N-terminal telopeptide of type I collagen as an early marker of fracture nonunion in rabbits. [pubmed:28105092]
Institute of Pharmacology Effects of long-term administration of pantoprazole on bone mineral density in young male rats. [pubmed:27552060]
Indian Journal of Orthopaedics N-terminal telopeptides of type I collagen and bone mineral density for early diagnosis ofnonunion: An experimental study in rabbits. [pubmed:27512225]
Biological Trace Element Research Micromolar Levels of Sodium Fluoride Promote Osteoblast Differentiation Through Runx2 Signaling [pubmed:28083749]
J Trace Elem Med Biol Effects of fluoride on insulin signaling and bone metabolism in ovariectomized rats. [pubmed:27908407]
Mater Sci Eng C Mater Biol Appl. Synthesis of polypyrrole nanowires with positive effect on MC3T3-E1 cell functions through electrical stimulation. [pubmed:27987727]
Biomedicine & Pharmacotherapy Anti-osteoporotic effects of an antidepressant tianeptine on ovariectomized rats [S0753332216322752]
Biological Trace Element Research Effect of Dietary Phytase Supplementation on Bone and Hyaline Cartilage Development of Broilers Fed with Organically Complexed Copper in a Cu-Deficient Diet [article:10.1007]
Revista Brasileira de Ciência Avícola Effect of Zinc Level and Source (Zinc Oxide Vs. Zinc Glycine) on Bone Mechanical and Geometric Parameters, and Histomorphology in Male Ross 308 Broiler Chicken [10.159:1806-9061-2016-0285]
Pharmacological Reports Oral administration of kaempferol inhibits bone loss in rat model of ovariectomy-induced osteopenia [pubmed:29031689]
Journal of Bone and Mineral Metabolism MiR‑142‑5p promotes bone repair by maintaining osteoblast activity [pubmed:27085967]
Oncotarget A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice. [pubmed:28060768]
Journal of Inorganic Biochemistry Biomimetic fabrication of antibacterial calcium phosphates mediated by polydopamine. [pubmed:29049953]
Biomedicine & pharmacotherapy Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation. [pubmed:28742995]
Asian Journal of Biomedical and Pharmaceutical Sciences A Water Extract of Benefiting-Bone Capsule Improves Osteoporosis via Transcriptional and Translational Regulation of Key Factors in Notch and Wnt/β-catenin Signaling Pathways in Ovariectomized Rats [ISSN 2249 – 622X]
Journal of Materials Chemistry B Stabilization of Ca-deficient hydroxyapatite in biphasic calcium phosphate ceramics by adding alginate to enhance their biological performances [10.1039/C7TB02620J ]
Journal of Cellular Physiology Osteogenic commitment and differentiation of human mesenchymal stem cells by low-intensity pulsed ultrasound stimulation. [pubmed:28621452]
Materials Science & Engineering C-Materials for Biological Applications BMP-2 gene transfection of bone marrow stromal cells to induce osteoblastic differentiation in a rat calvarial defect model [Pubmed:30033316]
Journal of Functional Foods Effect of long-term administration of mangiferin from on bone metabolism in ovariectomized rats [10.1016:j.jff.2018.04.048]
Journal of Ethnopharmacology Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model [Pubmed:29705515]
Life Sciences Myricetin ameliorates glucocorticoid-induced osteoporosis through the ERK signaling pathway [Pubmed:29883721]
PLoS One Subsequent somatic axis and bone tissue metabolism responses to a low-zinc diet with or without phytase inclusion in broiler chickens [Pubmed:29373588]
Royal Society of Chemistry Stabilization of Ca-deficient hydroxyapatite in biphasic calcium phosphate ceramics by adding alginate to enhance their biological performances [c7tb02620j]
Molecular Medicine Reports Effects of constrained dynamic loading, CKIP‑1 gene knockout and combination stimulations on bone loss caused by mechanical unloading [Pubmed:29956799]
Journal of Ultrasound in Medicine A Comparison of 1‐and 3.2‐MHz Low‐Intensity Pulsed Ultrasound on Osteogenesis on Porous Titanium Alloy Scaffolds: An In Vitro and In Vivo Study [Pubmed:29781183]
Tropical Animal Health and Production Dietary supplementation for Santa Inês hair ewes on pasture at pre-and postpartum periods: dry matter intake, digestibility, milk production, and mineral metabolism [Pubmed:29931604]
American Scientific Publishers Effects of KLD-12/Recombinant Human Bone Morphogenetic Protein-2 Nanofiber Scaffold on the Osteogenic Activity of Rabbit Bone Marrow Mesenchymal Stem Cells [10.1166:jbt.2018.1719]
Journal of Materials Chemistry B Enhanced osteoinductivity of porous biphasic calcium phosphate ceramic beads with high content of strontium incorporated calcium deficient hydroxyapatite [Doi: 10.1039/C8TB01554F]
International Journal of Clinical and Experimental Medicine Combined effect of pulsed electromagnetic fields and narrowband ultraviolet B on bone metabolism in glucocorticoid-treated rats []
Nanoscale Beta-Cyclodextrin Modified Mesoporous Bioactive Glass Nanoparticles/Silk Fibroin Hybrid Nanofibers as an Implantable Estradiol Delivery System for the Potential … [Pubmed: 30255905]
Carbon In Situ Self-Assembly of Graphene Oxide/Polydopamine/Sr2+ Nanosheets on Titanium Surfaces for Enhanced Osteogenic Differentiation of Mesenchymal Stem Cells [Doi: 10.1016/j.carbon.2018.10.081]
Experimental Gerontology The decline of whole-body glucose metabolism in ovariectomized rats [Pubmed: 30292771]
Tropical Journal of Pharmaceutical Research Mollugin attenuates glucocorticoid-induced osteoporosis in rats via Akt/P13K pathway []
Bone & Joint Research Transcriptome analysis of osteoblasts in an ovariectomized mouse model in response to physical exercise []
Bone Research NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts [Pubmed: 30455992]
ACS Applied Materials & Interfaces Osteoinductivity of porous biphasic calcium phosphate ceramic spheres with nanocrystalline and their efficacy in guiding bone regeneration [Pubmed: 30629405]
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS CoCr porous scaffolds manufactured via selective laser melting in orthopedics: Topographical, mechanical, and biological characterization [Pubmed: 30689288]
Chemico-Biological Interactions Lead exposure inhibits osteoblastic differentiation and inactivates the canonical Wnt signal and recovery by icaritin in MC3T3-E1 subclone 14 cells [Pubmed: 30731080]
Phytomedicine Effect and mechanism of psoralidin on promoting osteogenesis and inhibiting adipogenesis [Doi: 10.1016/j.phymed.2019.152860]
Advanced Healthcare Materials Impact of Hydrogel Elasticity and Adherence on Osteosarcoma Cells and Osteoblasts [Pubmed: 30838809]
American Journal of Translational Research Long non-coding RNA SNHG7 promotes the fracture repair through negative modulation of miR-9 []
Journal of Orthopaedic Surgery and Research Macrophage inhibits the osteogenesis of fibroblasts in ultrahigh molecular weight polyethylene (UHMWPE) wear particle-induced osteolysis []
Toxicol Ind Health Influence of physical training on markers of bone turnover, mechanical properties, morphological alterations, density and mineral contents in the femur of rats exposed … [Pubmed: 30983556]
Tropical Journal of Pharmaceutical Research Methylbenzoxime as a therapeutic agent for glucocorticoid-induced osteoporosis in rats. []
medical science monitor Silent Mating Type Information Regulation 2 Homolog (SIRT1) Influences Osteogenic Proliferation and Differentiation of MC3T3-E1 Cells via Regulation of miR-132 … [Pubmed: 30923307]
Toxicology and applied pharmacology Alpha ketoglutarate exerts a pro-osteogenic effect in osteoblast cell lines through activation of JNK and mTOR/S6K1/S6 signaling pathways [Pubmed: 31051157]
Journal of Innovations in Pharmaceutical and Biological Sciences Preventive effect of dried plum extract against dexamethasone-induced osteoporosis in male rats through inhibiting cathepsin-K activity, lipogenesis and … []
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A A dual functional bone‐defect‐filling material with sequential antibacterial and osteoinductive properties for infected bone defect repair [Pubmed: 31173657]
Polymers Use of Polyphenol Tannic Acid to Functionalize Titanium with Strontium for Enhancement of Osteoblast Differentiation and Reduction of Osteoclast Activity [Pubmed: 31362449]
Bulletin of Experimental Biology and Medicine Laboratory Monitoring of Bone Tissue Remodeling after Augmentation of Impression Intraarticular Fracture with Different Types of Bone Graft [Pubmed: 31630302]
International Journal of Nanomedicine Nano-Hydroxyapatite Coating Promotes Porous Calcium Phosphate Ceramic-Induced Osteogenesis Via BMP/Smad Signaling Pathway [Pubmed: 31632013]
Molecular Therapy-Nucleic Acids AAV-anti-miR-214 prevents collapse of the femoral head in osteonecrosis by regulating osteoblast and osteoclast activities [Pubmed: 31739209]
International Journal of Environmental Research and Public Health Alleviating Effect of α-Lipoic Acid and Magnesium on Cadmium-Induced Inflammatory Processes, Oxidative Stress and Bone Metabolism Disorders in Wistar Rats [Pubmed: 31739465]
Pharmacology MiR-296 Promotes Osteoblast Differentiation by Upregulating Cbfal [Pubmed: 31694033]
Brazilian Journal of Medical and Biological Research Beneficial effects of Cuscuta chinensis extract on glucocorticoid-induced osteoporosis through modulation of RANKL/OPG signals [Pubmed: 31826180]
Biomedicine & Pharmacotherapy Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss [Pubmed: 31846839]
Journal of Bone and Mineral Research BMP9 reduces bone loss in ovariectomized mice by dual regulation of bone remodeling [Pubmed: 31914211]
Theranostics EDTA-Modified 17β-Estradiol-Laden Upconversion Nanocomposite for Bone-Targeted Hormone Replacement Therapy for Osteoporosis [Pubmed: 32194868]
Journal of Korean Neurosurgical Society Rutin Improves Bone Histomorphometric Values by Reduction of Osteoclastic Activity in Osteoporosis Mouse Model Induced by Bilateral Ovariectomy [Pubmed: 32172552]
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A Positive role of calcium phosphate ceramics regulated inflammation in the osteogenic differentiation of mesenchymal stem cells [Pubmed: 32064734]
CELL BIOCHEMISTRY AND FUNCTION HSP90 inhibitors strengthen extracellular ATP‐stimulated synthesis of interleukin‐6 in osteoblasts: Amplification of p38 MAP kinase [Pubmed: 32567086]
Cell Death & Disease QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism [Pubmed: 32382069]
Molecular Medicine Reports Neuropeptide Y upregulates Runx2 and osterix and enhances osteogenesis in mouse MC3T3‑E1 cells via an autocrine mechanism [Pubmed: 33000198]
Food & Function Comparative study of DHA-enriched phosphatidylcholine and EPA-enriched phosphatidylcholine on ameliorating high bone turnover via regulation of the … [Pubmed: 33140795]
ADVANCED FUNCTIONAL MATERIALS A Hierarchical Janus Nanofibrous Membrane Combining Direct Osteogenesis and Osteoimmunomodulatory Functions for Advanced Bone Regeneration []
Revista Argentina de Clínica Psicológica Research on the Mechanism of miR-142-5p's Promotion of the Function and Mineralization of Osteoblasts by Down-regulating the Expression of WWP1 Gene []
淫羊藿水提物及提取药渣的抗骨质疏松药效比较研究 []
Chemical Engineering Journal Bioinspired polydopamine/graphene oxide/collagen nanofilms as a controlled release carrier of bioactive substances []
Surfaces and Interfaces In vitro comparison of titanium surface conditioning via boron-compounds and sand-blasting acid-etching []
J Bone Miner Res Lgr4 promotes aerobic glycolysis and differentiation in osteoblasts via the canonical Wnt/¦Â©\catenin pathway [33950533]
Biochemical Engineering Journal Studies of osteoblast-like MG-63 cellular proliferation and differentiation with cyclic stretching cell culture system on biomimetic hydrophilic layers modified polydimethylsiloxane substrate []
Br J Pharmacol Andrographolide prevents bone loss via targeting ERRalpha‐regulated metabolic adaption of osteoclastogenesis [34233019]
PHARMACEUTICAL BIOLOGY Effects of icariin on the fracture healing in young and old rats and its mechanism [34511043]
Evid Based Complement Alternat Med Gujiansan Ameliorates Avascular Necrosis of the Femoral Head by Regulating Autophagy via the HIF-1α/BNIP3 Pathway [34512780]
ACS Appl Mater Interfaces Spatiotemporal Management of the Osteoimmunomodulation of Fibrous Scaffolds by Loading a Novel Amphiphilic Nanomedicine [Pubmed:35311248]
Molecules Notoginsenoside R1 Promotes Migration, Adhesin, Spreading, and Osteogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stromal Cells [Pubmed:35684342]
Journal of Exercise Science & Fitness Effects of 8-week High-Intensity Interval Training and Moderate-Intensity Continuous Training on Bone Metabolism in Sedentary Young Females [Pubmed:35096081]
Journal of Bionic Engineering Effect of Antibacterial Enoxacin on the Properties of Injectable Nano-hydroxyapatite/Polyurethane Cement for Bone Repairing []
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