白介素6(IL6)检测试剂盒(酶联免疫吸附试验法,高敏型)

High Sensitive ELISA Kit for Interleukin 6 (IL6)

MGI2-A; MGI2A; HGF; BSF2; HSF; IFNB2; B-Cell Stimulatory Factor-2; Hybridoma/Plasmacytoma Growth Factor; Hepatocyte Stimulating Factor; Cytotoxic T-Cell Differentiation Factor

  • 白介素6(IL6)检测试剂盒(酶联免疫吸附试验法,高敏型) 产品包装(模拟)
  • 白介素6(IL6)检测试剂盒(酶联免疫吸附试验法,高敏型) 产品包装(模拟)
  • 白介素6(IL6)检测试剂盒(酶联免疫吸附试验法,高敏型) 实验结果图
  • HEA079Hu.jpg 标准曲线图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

本试剂盒用于检测白介素6(IL6),经检测与其它相似物质无明显交叉反应。
由于受到技术及样本来源的限制,不可能完成对所有相关或相似物质交叉反应检测,因此本试剂盒有可能与未经检测的其它物质有交叉反应。

回收率

分别于定值血清及血浆样本中加入一定量的白介素6(IL6)(加标样品),重复测定并计算其均值,回收率为测定值与理论值的比率。

样本 回收率范围(%) 平均回收率(%)
serum(n=5) 95-102 99
EDTA plasma(n=5) 78-89 84
heparin plasma(n=5) 97-104 101

精密度

精密度用样品测定值的变异系数CV表示。CV(%) = SD/mean×100
批内差:取同批次试剂盒对低、中、高值定值样本进行定量检测,每份样本连续测定20 次,分别计算不同浓度样本的平均值及SD值。
批间差:选取3个不同批次的试剂盒分别对低、中、高值定值样本进行定量测定,每个样本使用同一试剂盒重复测定8次,分别计算不同浓度样本的平均值及SD值。
批内差: CV<10%
批间差: CV<12%

线性

在定值血清及血浆样本内加入适量的白介素6(IL6),并倍比稀释成1:2,1:4,1:8,1:16的待测样本,线性范围即为稀释后样本中白介素6(IL6)含量的测定值与理论值的比率。

样本 1:2 1:4 1:8 1:16
serum(n=5) 95-102% 93-101% 84-92% 82-95%
EDTA plasma(n=5) 79-105% 95-103% 92-101% 91-99%
heparin plasma(n=5) 88-102% 83-104% 80-96% 98-105%

稳定性

经测定,试剂盒在有效期内按推荐温度保存,其活性降低率小于5%。
为减小外部因素对试剂盒破坏前后检测值的影响,实验室的环境条件需尽量保持一致,尤其是实验室内温度、湿度及温育条件。其次由同一实验员来进行操作可减少人为误差。

试剂盒内容

试剂名称 数量 试剂名称 数量
96孔板(预包被) 1 96孔板覆膜 4
标准品 2 标准品稀释液 1×20mL
检测溶液A 1×120µL 检测稀释液A 1×12mL
检测溶液B 1×120µL 检测稀释液B 1×12mL
TMB底物 1×9mL 终止液 1×6mL
浓洗涤液 (30 × concentrate) 1×20mL 说明书 1

实验流程

1. 实验前标准品、试剂及样本的准备;
2. 加样(标准品及样本)100µL,37°C孵育1小时;
3. 吸弃,加检测溶液A100µL,37°C孵育1小时;
4. 洗板3次;
5. 加检测溶液B100µL,37°C孵育30分钟;
6. 洗板5次;
7. 加TMB底物90µL,37°C孵育10-20分钟;
8. 加终止液50µL,立即450nm读数。

High Sensitive ELISA Kit for Interleukin 6 (IL6)

实验原理

将白介素6(IL6)抗体包被于96孔微孔板中,制成固相载体,向微孔中分别加入标准品或标本,其中的白介素6(IL6)与连接于固相载体上的抗体结合,然后加入生物素化的白介素6(IL6)抗体,将未结合的生物素化抗体洗净后,加入HRP标记的亲和素,再次彻底洗涤后加入TMB底物显色。TMB在过氧化物酶的催化下转化成蓝色,并在酸的作用下转化成最终的黄色。颜色的深浅和样品中的白介素6(IL6)呈正相关。用酶标仪在450nm波长下测定吸光度(O.D.值),计算样品浓度。

相关产品

编号 适用物种:Homo sapiens (Human,人) 应用(仅供研究使用,不用于临床诊断!)
APA079Hu01 白介素6(IL6)活性蛋白 Cell culture; Activity Assays.
APA079Hu61 白介素6(IL6)活性蛋白 Cell culture; Activity Assays.
EPA079Hu61 白介素6(IL6)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPA079Hu01 白介素6(IL6)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA079Hu06 白介素6(IL6)多克隆抗体 WB; IHC; ICC; IP.
PAA079Hu01 白介素6(IL6)多克隆抗体 WB; IHC; ICC; IP.
LAA079Hu71 白介素6(IL6)多克隆抗体(生物素标记) WB; IHC; ICC.
MAA079Hu22 白介素6(IL6)单克隆抗体 WB; IHC; ICC; IP.
LAA079Hu72 白介素6(IL6)单克隆抗体(生物素标记) WB; IHC; ICC.
SEA079Hu 白介素6(IL6)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.
HEA079Hu 白介素6(IL6)检测试剂盒(酶联免疫吸附试验法,高敏型) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA079Hu 白介素6(IL6)检测试剂盒(化学发光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
PSA079Hu01 白介素6(IL6)抗体对 ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSA079Hu01 白介素6(IL6)检测试剂盒DIY材料(酶联免疫吸附试验法) Main materials for "Do It (ELISA Kit) Yourself".

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Molecular Immunology Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by reCavia (Guinea pig )lating caveolin-1 through TLR2/MyD88/NF-ŚĘB in murine model of asthma [Pubmed:27289030]
Hepatology Research Amelioration of free fatty acid-induced fatty liver by quercetin-3-O-β-D-glucuronide through modulation ofperoxisome proliferator-activated receptor-alpha/sterol reCavia (Guinea pig )latory element-binding protein-1c signaling. [Pubmed:26190035]
Biomedicine & Pharmacotherapy Investigation of the anti-glioma activity of Oviductus ranae protein hydrolysate [Pubmed:27261592]
Livestock Science Dynamics of salivary immunoglobulin A and serum interleukin 6 levels in newborn calves [science:S1871141316300841]
Journal of Dairy Science Serum interleukin-6 as a prognostic marker in neonatal calf diarrhea [Pubmed:27209135]
Animal Anterior pituitary influence on adipokine expression and secretion by porcine adipocytes. [Pubmed:27074715]
International Immunopharmacology Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery [Pubmed:26802602]
Mediators of Inflammation Plasma Periostin Levels Are Increased in Chinese Subjects with Obesity and Type 2 Diabetes and Are Positively Correlated with Glucose and Lipid Parameters [journals:6423637]
Biol Trace Elem Res. Analysis of Ionomic Profiles of Canine Hairs Exposed to Lipopolysaccharide (LPS)-Induced Stress [Pubmed:26758868]
Endocrine Effects of glucagon-like peptide-1 on advanced glycation endproduct-induced aortic endothelial dysfunction in streptozotocin-induced diabetic rats: possible roles of Rho kinase- and AMP kinase-mediated nuclear factor κB signaling pathways [Pubmed:26758998]
Am J Physiol Gastrointest Liver Physiol Inhibition of cyclooxygenase-2 alleviates liver cirrhosis via improvement of the dysfunctional Cavia (Guinea pig )t-liver axis in rats [Pubmed:27056726]
Biosensors and Bioelectronics Ultrasensitive photoelectrochemical immunoassay for CA19-9 detection based on CdSe@ZnS quantum dots sensitized TiO2NWs/Au hybrid structure amplified by quenching effect of Ab2@V2+ conjugates [science:S0956566315304474]
Journal of Veterinary Research Comparison of laparoscopic and traditional abomasal cannulation in sheep [view:16]
Basic Clin Pharmacol Toxicol Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats [Pubmed:26833867]
Food Funct The effects of polysaccharides from the root of Angelica sinensis on tumor growth and iron metabolism in H22-bearing mice [Pubmed:26757699]
J Neurochem. Anti‐inflammatory properties of tianeptine on lipopolysaccharide‐induced changes in microglial cells involve toll‐like receptor‐related pathways [Pubmed:26640965]
Virol J Classical swine fever virus NS5A protein changed inflammatory cytokine secretion in porcine alveolar macrophages by inhibiting the NF-κB signaling pathway [Pubmed:27296632]
Arch Anim Nutr The effect of dietary methionine levels on fattening performance and selected blood and tissue parameters of turkeys [Pubmed:26829577]
Journal of Agricultural Biotechnology Gln Attenuates LPS-induced Inflammatory Injury of Bos taurus Testis Sustentacular Cells [10610]
Front Pharmacol Poria Attenuates Idiosyncratic Liver Injury Induced by Polygoni Multiflori Radix Praeparata [pubmed:27803670]
Oxidative Medicine and Cellular Longevity Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation. [pubmed:27656261]
Journal of Applied Life Sciences International Vitamins C and E Alleviate Nephrotoxicity-induced by Potassium Bromate in Rats [Barakat812016JALSI28698.pdf]
journal of molecular and cellular cardiology Mutant DD genotype of NFKB1 gene is associated with the susceptibility and severity of coronary artery disease. [pubmed:28088561]
BMC Complementary and Alternative Medicine Effect of traditional Chinese medicine formula Sinisan on chronic restraint stress-induced nonalcoholic fatty liver disease: a rat study. [pubmed:28388904]
immunology letters Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila. [pubmed:28366526]
Lipids in Health and Disease Protective effects of various ratios of DHA/EPA supplementation on high-fat diet-induced liver damage in mice. [pubmed:28356106]
Journal of Functional Foods Eicosapentaenoic acid-enriched phospholipids improve atherosclerosis by mediating cholesterol metabolism [S1756464617300890]
Nutrition. Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats. [pubmed:27908549]
Atherosclerosis Iridoid-loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs expression and inflammation. [pubmed:27744131]
Journal of Diabetes Research Plasma C1q/TNF-Related Protein-3 (CTRP-3) and High-Mobility Group Box-1 (HMGB-1) Concentrations in Subjects with Prediabetes and Type 2 Diabetes [pubmed:27738641]
Andrology Chronic prostatitis/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis … [doi:10.1111]
Molecular Immunology Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma [pubmed:27289030]
Cellular Physiology and Biochemistry The Neuroprotective Effect of Puerarin in Acute Spinal Cord Injury Rats. [pubmed:27576607]
World Journal of Gastroenterology  Alterations in gut microbiota during remission and recurrence of diabetes after duodenal-jejunal bypass in rats [pubmed:27547013]
Effect of Passion Fruit (Passiflora edulis f. flavicarpa deg.) Peel Flour on the Prognosis of Acute Pancreatitis after Overnutrition During Lactation Effect of Passion Fruit (Passiflora edulis f. flavicarpa deg.) Peel Flour on the Prognosis of Acute Pancreatitis after Overnutrition During Lactation [art00008]
Journal of Orthopaedic Surgery and Research  No midterm advantages in the middle term using small intestinal submucosa and human amniotic membrane in Achilles tendon transverse tenotomy [pubmed:27881176]
Atherosclerosis Iridoid–loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs … [S0021915016314046]
Molecular Medicine Reports C‑reactive protein/oxidized low density lipoprotein/β2‑glycoprotein i complexes induce lipid accumulation and inflammatory reaction in macrophages via p38/mitogen‑ … [10.3892]
网页打不开 The role of RhoA/ROCK singal pathway in cardiac rupture after infarction [:]
Poultry Science ALV-J strain SCAU-HN06 induces innate immune responses in chicken primary monocyte-derived macrophages [pubmed:27486255]
Physiological Research Lung inflammatory and oxidative alterations after exogenous surfactant therapy fortified with budesonide in rabbit model of meconium aspiration syndrome. [pubmed:28006947]
PLOS ONE S-Propargyl-Cysteine, a Novel Hydrogen Sulfide Donor, Inhibits Inflammatory Hepcidin and Relieves Anemia of Inflammation by Inhibiting IL-6/STAT3 Pathway. [pubmed:27649298]
PLOS ONE Protective Effects of Bifidobacterium on Intestinal Barrier Function in LPS-Induced EnterocyteBarrier Injury of Caco-2 Monolayers and in a Rat NEC Model. [pubmed:27551722]
Polish journal of veterinary sciences Acute phase response in the primiparous dairy cows after repeated percutaneous liver biopsyduring the transition period. [pubmed:27487515]
BMC Veterinary Research Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritisphenotype and progression in Standardbred racehorses over five years of racing career. [pubmed:27821120]
Journal of Physiology and Pharmacology Effects of budesonide on the lung functions, inflammation and apoptosis in a saline-lavagemodel of acute lung injury. [pubmed:28195073]
BioMed Research International Dihydromyricetin Protects against Diabetic Cardiomyopathy in Streptozotocin-Induced DiabeticMice. [pubmed:28421194]
Saudi Journal of Gastroenterology Deoxyschizandrin suppresses dss-induced ulcerative colitis in mice. [pubmed:27976641]
Parasites & Vectors Vaccination of rabbits with immunodominant antigens from Sarcoptes scabiei induced highlevels of humoral responses and pro-inflammatory cytokines but confers limited protection. [pubmed:27502394]
Oncotarget Poly(ADP-ribose) polymerase 1 inhibition protects cardiomyocytes from inflammation andapoptosis in diabetic cardiomyopathy. [pubmed:27027354]
Life Sciences Bone fracture healing is delayed in splenectomic rats [pubmed:27956350]
Food Funct. Flavonoids from sea buckthorn inhibit the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through the MAPK and NF-κB pathways. [pubmed:28256654]
Cell Death Dis. Salusin-β contributes to oxidative stress and inflammation in diabetic cardiomyopathy [pubmed:28333148]
Biomedicine & pharmacotherapy= Biomedecine & pharmacotherapie Protective effects of N-acetylcystein and atorvastatin against renal and hepatic injury in a rat model of intestinal ischemia-reperfusion [pubmed:28273631]
Procalcitonin und proinflammatorische Zytokine in der bronchoalveolären Lavage beim lungenkranken Pferd unter inhalativer Glukokortikoidtherapie [FUDISS_thesis_000000103830]
International Journal of Stem Cell Research and Transplantation Protective Role of Bone Marrow Derived Mesenchymal Stem Cells-Conditioned Medium in the Infarcted Myocardium: The Potential Role of Selected Cytokines [IJST-2328-3548-04-803]
Kidney Research and Clinical Practice The role of local IL6/JAK2/STAT3 signaling in high glucose–induced podocyte hypertrophy [S2211913216300912]
Домашня сторінка ВПЛИВ КРОВОВТРАТИ НА ДИНАМІКУ ВМІСТУ ЦИТОКІНІВ СИРОВАТКИ КРОВІ В ПЕРІОД ГОСТРОЇ РЕАКЦІЇ НА КРАНІОСКЕЛЕТНУ ТРАВМУ [83646]
Journal of Vascular Research Transplantation of Autologous Bone Marrow Mononuclear Cells Regulates Inflammation in aRabbit Model of Carotid Artery Atherosclerosis. [pubmed:27788500]
Neural regeneration research Breviscapine reduces neuronal injury caused by traumatic brain injury insult: partly associated with suppression of interleukin-6 expression [pubmed:28250753]
The Royal Society of Chemistry The positive role of macrophage secretion stimulated by BCP ceramic in the ceramic-induced osteogenic differentiation of pre-osteoblasts via Smad-related signaling pathways [c6ra23362g]
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