核因子κB受体激活因子配体(RANkL)多克隆抗体

Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B Ligand (RANkL)

CD254; TNFSF11; ODF; OPGL; TRANCE; HRANKL2; SOdf; Tumor Necrosis Factor(ligand)superfamily Member 11; TNF-related activation-induced cytokine

  • 核因子κB受体激活因子配体(RANkL)多克隆抗体 产品包装(模拟)
  • 核因子κB受体激活因子配体(RANkL)多克隆抗体 产品包装(模拟)
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对RANkL的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别RANkL。

用法

免疫印迹：0.2-2µg/mL;1:250-2500
免疫组织化学：5-20µg/mL;1:25-100
免疫细胞化学：5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。

赠品

相关产品

编号 适用物种：Chicken (Gallus，鸡) 应用(仅供研究使用，不用于临床诊断！)
URPA855Ga01 核因子κB受体激活因子配体(RANkL)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
UPAA855Ga01 核因子κB受体激活因子配体(RANkL)多克隆抗体 WB; IHC; ICC; IP.

参考文献

杂志 参考文献
Archives of Oral Biology Compressive stress induced the up-regulation of M-CSF, RANKL, TNF-α expression and the down-regulation of OPG expression in PDL cells via the integrin-FAK pathway [ScienceDirect: S0003996912003998]
PLOS One Adipokines in Psoriatic Arthritis Patients: The Correlations with Osteoclast Precursors and Bone Erosions [PubMed: PMC3483160]
Arthritis Research&Therapy Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes [PubMed: PMC3672788]
International Journal of Oral and Maxillofacial Surgery The effects of chronic zoledronate usage on the jaw and long bones evaluated using RANKL and osteoprotegerin levels in an animal model [Pubmed: 23522850]
AGE Estrogen deficiency does not decrease the in vitro osteogenic potential of rat adipose-derived mesenchymal stem cells [Pubmed: 24687841]
Food Science & Nutrition Effects and mechanisms of 8-prenylnaringenin on osteoblast MC3T3-E1 and osteoclast-like cells RAW264.7 [Onlinelibrary: fsn3.109]
Food Sci Nutr. Effects and mechanisms of 8‐prenylnaringenin on osteoblast MC3T3‐E1 and osteoclast‐like cells RAW264. 7 [Pubmed:Pmc4221832]
Journal of Investigative Surgery Effect of Nicotine on RANKL and OPG and Bone Mineral Density [Pubmed:24830656]
Int J Mol Med. Effects of icariin on the regulation of the OPG?RANKL?RANK system are mediated through the MAPK pathways in IL?1β?stimulated human SW1353 chondrosarcoma … [Pubmed:25270538]
Clinical and Experimental Pharmacology and Physiology Carvedilol promotes neurological function, reduces bone loss and attenuates cell damage after acute spinal cord injury in rats [Pubmed:25424914]
Int J Clin Exp Pathol A novel model of bisphosphonate-related osteonecrosis of the jaw in rats [PubMed: 26191212]
oncotarget MicroRNA-106b inhibits osteoclastogenesis and osteolysis by targeting RANKL in giant cell tumor of bone [PubMed: 26053181]
European Journal of Clinical Investigation Serum osteopontin levels are upregulated and predict disability after an ischaemic stroke [PubMed: 25845543]
Scienze Biomediche Effetti del laser a bassa dose su cellule osteoblastiche [INCERTIPARENTI_SERENA_TESI.pdf]
Nutrition. Noni leaf and black tea enhance bone regeneration in estrogen-deficient rats. [pubmed:27908549]
PLoS One. Extracorporeal shock waves alone or combined with raloxifene promote bone formation and suppress resorption in ovariectomized rats. [pubmed:28158228]
Epilepsy Research The effect of lamotrigine and phenytoin on bone turnover and bone strength: A prospective study in Wistar rats [pubmed:27838501]
Int Endod J.  Odontoclastogenesis of mouse papilla-derived MDPC-23 cells induced by lipopolysaccharide. [pubmed:28333374]
Sci Rep.  Sprint Interval Training Induces A Sexual Dimorphism but does not Improve Peak Bone Mass in Young and Healthy Mice. [pubmed:28303909]
Sci Rep. Skeletal Site-specific Effects of Zoledronate on in vivo Bone Remodeling and in vitro BMSCs Osteogenic Activity. [pubmed:28139685]
Biomedicine & Pharmacotherapy Anti-osteoporotic effects of an antidepressant tianeptine on ovariectomized rats [S0753332216322752]
BMJ Journals SAT0003 The Role of 12/15-Lipoxygenase in The Pathogenesis of Osteoporosis in Mice [content:75]
Japanese Society for Bone and Mineral Research Allogeneic yet major histocompatibility complex‑matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced trabecular bone [article:10.1007]
ONCOLOGY LETTERS Assessment of bone metabolism and biomechanical properties of the femur, following treatment with anastrozole and letrozole in an experimental model of menopause [ol.2017.6596]
Journal of Clinical Periodontology  Peroxisome proliferator‐activated receptor γ plays dual roles on experimental periodontitis in rats [Pubmed:29574908]
Journal of Functional Foods Effect of long-term administration of mangiferin from on bone metabolism in ovariectomized rats [10.1016:j.jff.2018.04.048]
International Immunopharmacology Switched memory B cells promote alveolar bone damage during periodontitis: An adoptive transfer experiment [Pubmed:30015235]
European Journal of Pharmacology The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism [Pubmed:29428468]
Journal of Bone and Mineral Metabolism Allogeneic yet major histocompatibility complex-matched bone marrow transplantation in mice results in an impairment of osteoblasts and a significantly reduced … [Pubmed:28766138]
Experimental and Therapeutic Medicine Liraglutide exerts a bone‑protective effect in ovariectomized rats with streptozotocin‑induced diabetes by inhibiting osteoclastogenesis [Pubmed:29805533]
Bone The sole and combined effect of simvastatin and platelet rich fibrin as a filling material in induced bone defect in tibia of albino rats [Pubmed: 30208342]
Journal of Periodontal Research Improved RANKL expression and osteoclastogenesis induction of CD27+ CD38− memory B cells: A link between B cells and alveolar bone damage in periodontitis [Pubmed: 30346027]
Bone Research NUMB maintains bone mass by promoting degradation of PTEN and GLI1 via ubiquitination in osteoblasts [Pubmed: 30455992]
Journal of International Dental and Medical Research Alendronate Effect in RANKL Concentration at Ovariectomized Sprague Dawley Rat. []
Bone Development and characterization of supramolecular calcitonin assembly and assessment of its interactions with the bone remodelling process [Pubmed: 30797058]
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology Evaluation of therapeutic effects of teriparatide in a rat model of zoledronic acid-induced bisphosphonate-related osteonecrosis []
Rheumatology International Comparison of RANKL expression, inflammatory markers, and cardiovascular risk in patients with acute coronary syndrome with and without rheumatoid arthritis [Pubmed: 31297563]
World Journal of Pediatrics Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis [Pubmed: 31641939]
Bone Mice lacking plastin-3 display a specific defect of cortical bone acquisition [Pubmed: 31678489]
BIOSCIENCE REPORTS IL-38 restrains inflammatory response of collagen-induced arthritis in rats via SIRT1/HIF-1α signaling pathway [Pubmed: 32347300]
Journal of Ethnopharmacology Anti-osteoporosis effect of Semen Cuscutae in ovariectomized mice through inhibition of bone resorption by osteoclasts [34801609]
Br J Haematol Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment [Pubmed:34954822]
Biomed Pharmacother Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis [Pubmed:35453007]
Phytomedicine Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK … [Pubmed:35660352]
Med Science Identification of marker proteins in preterm and term birth: Relationship of rankl and HSP70 in the cord blood []
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