分泌型卷曲相关蛋白5(SFRP5)多克隆抗体
Polyclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)
SARP3; Secreted Apoptosis Related Protein 3; Frizzled-related protein 1b
- 编号UPAC842Hu02
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源多抗制备
- 宿主兔
- 效价-
- Ig类型 IgG
- 纯化方式抗原特异性亲和纯化
- 标记物无标记物
- 免疫原 -
- 缓冲液成份磷酸盐缓冲液(pH7.4, 含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.)
- 性状液体
- 浓度500µg/mL
- 且适物种-
- 应用WB
 如果抗体需用于流式细胞术,请参见流式抗体。
- 下载 英文说明书 中文说明书
- 规格 20µl100µl 200µl 1ml 10ml
- 价格 ¥ 315 ¥ 735 ¥ 1050 ¥ 2625 ¥ 10500
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特异性
该抗体是针对SFRP5的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SFRP5。
用法
            
                        免疫印迹:0.2-2µg/mL;1:250-2500
                        
 免疫组织化学:5-20µg/mL;1:25-100
                        
 免疫细胞化学:5-20µg/mL;1:25-100
                        
 最佳稀释倍数最终由用户决定。
                        
        
储存
经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
赠品
增值服务
相关产品
| 编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) | 
| URPC842Hu01 | 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPC842Hu02 | 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPC842Hu03 | 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| UPAC842Hu01 | 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 | IHC | 
| UPAC842Hu03 | 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 | WB | 
| UPAC842Hu02 | 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 | WB | 
| ULAC842Hu71 | 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记) | WB | 
| UMAC842Hu22 | 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体 | WB; IHC; ICC; IP. | 
| ULAC842Hu72 | 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体(生物素标记) | WB; IHC; ICC. | 
| USEC842Hu | 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| UWEC842Hu | 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法,宽范围) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| UHEC842Hu | 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法,高敏型) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| ULMC842Hu | 分泌型卷曲相关蛋白5(SFRP5)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. | 
参考文献
| 杂志 | 参考文献 | 
| Diabetes Research and Clinical Practice | Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance [PubMed: 23290274] | 
| European Journal of Clinical Investigation | Sfrp5 correlates with insulin resistance and oxidative stress [PubMed: 23398169] | 
| Pediatric Research | Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children [Pubmed: 24603290] | 
| Clin Endocrinol (Oxf). | SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children [Pubmed: 24330025] | 
| The Journal of Clinical Endocrinology & Metabolism | Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans [Pubmed: 23185036] | 
| Atherosclerosis | Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease [Pubmed: 24530778] | 
| PLoS One. | Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation [Pubmed:Pmc4072672] | 
| J Clin Endocrinol Metab. | Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation [Pubmed:24840810] | 
| Oncology Letters | Serum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma [Pubmed:25120720] | 
| Diabetes Metab Res Rev. | Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls [Pubmed:25139699] | 
| Clinical & Experimental Immunology | The wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis [Pubmed:25382802] | 
| Diabetes Metab Res Rev | Circulating SFRP5 levels are elevated in drug-na [PubMed: 25139699] | 
| J Matern Fetal Neonatal Med | Prediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels [PubMed: 26100762] | 
| Eur J Clin Invest | Sfrp5 associates with beta-cell function in humans [Pubmed:27019073] | 
| Osteoporosis International | Bone marrow sFRP5 level is negatively associated with bone formation markers [pubmed:27986984] | 
| Diabetes/Metabolism Research and Reviews | Plasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults [pubmed:28303637] | 
| Cardiovascular Diabetology | Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study [pubmed:28851362] | 
| Arteriosclerosis, Thrombosis, and Vascular Biology | Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With … [Pubmed:29674475] | 
| Obesity | Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans [Pubmed:29427376] | 
| J Bas Res Med Sci | Decreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats [article-1-352-en.pdf] | 
| Molecular Biology Reports | The effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome [Pubmed: 30194556] | 
| Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling [] | |
| British Journal Of Nutrition | A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile [Pubmed: 30375290] | 
| J Clin Endocrinol Metab | Role of wnt5a in Metabolic Inflammation in Humans [Pubmed: 30137542] | 
| Frontiers in Endocrinology | Association of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients [Pubmed: 32300333] | 
| CLINICAL BIOCHEMISTRY | Sfrp5/Wnt5a and Leptin/adiponectin levels in the serum and the periarterial adipose tissue of patients with peripheral arterial occlusive disease [Pubmed: 33188773] | 
| Sao Paulo Medical Journal | Association of serum levels of secreted frizzled-related protein 5 and Wnt member 5a with glomerular filtration rate in patients with type 2 diabetes mellitus and … [Pubmed: 32491086] | 
| Kidney Blood Press Res | Secreted Frizzled-Related Protein 5 Ameliorates Vascular Calcification in a Rat Model of Chronic Kidney Disease through the Wnt/β-Catenin Pathway [34469882] | 
| Cytokine | Association of serum uromodulin with adipokines in dependence of type 2 diabetes [34920231] | 
| PLoS One | Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study [Pubmed:34990470] | 
| JMIR Res Protoc | Investigating New Sensory Methods Related to Taste Sensitivity, Preferences, and Diet of Mother-Infant Pairs and Their Relationship With Body Composition … [Pubmed:35475790] | 
| Diabetology | Early Pregnancy Serum Concentration of Secreted Frizzled-Related Protein 4, Secreted Frizzled-Related Protein 5, and Chemerin in Obese Women Who Develop … [] | 
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