β-位淀粉样前体蛋白裂解酶1(bACE1)真核蛋白
Eukaryotic Beta-Site APP Cleaving Enzyme 1 (bACE1)
ASP2; Beta Secretase; Memapsin 2; Aspartyl protease 2; Beta-site amyloid precursor protein cleaving enzyme 1; Membrane-associated aspartic protease 2
- 编号UEPA718Mu61
- 物种Mus musculus (Mouse，小鼠) 相同的名称，不同的物种。
- 来源真核表达
- 宿主CHO
- 内毒素水平<1.0EU/µg(LAL法测定)
- 亚细胞定位细胞膜, 溶酶体, 高尔基体, 内质网腔
- 预测分子量50.01kDa
- 实际分子量75kDa(差异分析请参阅说明书)
- 片段与标签Thr22~Thr457 with N-terminal His Tag
- 缓冲液成份PBS, pH7.4, containing 5% Trehalose.
- 性状冻干粉
- 纯度> 90%
- 等电点5.0
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应用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，请参见活性蛋白。 - 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 576 ¥ 1440 ¥ 2880 ¥ 8640 ¥ 21600
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产品包装(模拟)
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产品包装(模拟)
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通过ISO 9001、ISO 13485质量体系认证
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月，-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定，具体方法如下：在37°C孵育48小时，没有显著的降解或者沉淀产生。保质期内，在适当的条件下存储，损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种：Mus musculus (Mouse，小鼠) | 应用(仅供研究使用，不用于临床诊断！) |
| URPA718Mu02 | β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA718Mu01 | β-位淀粉样前体蛋白裂解酶1(bACE1)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA718Mu61 | β-位淀粉样前体蛋白裂解酶1(bACE1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA718Mu01 | β-位淀粉样前体蛋白裂解酶1(bACE1)多克隆抗体 | WB |
| UPAA718Mu02 | β-位淀粉样前体蛋白裂解酶1(bACE1)多克隆抗体 | WB; IHC; ICC; IP. |
| USEA718Mu | β-位淀粉样前体蛋白裂解酶1(bACE1)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| ULMA718Mu | β-位淀粉样前体蛋白裂解酶1(bACE1)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. |
参考文献
| 杂志 | 参考文献 |
| Food & Function | Comparative study of the effects of phosphatidylcholine rich in DHA and EPA on Alzheimer’s disease and the possible mechanisms in CHO-APP/PS1 cells and SAMP8 mice [pubmed:29292421] |
| Journal of Functional Foods | EPA enriched ethanolamine plasmalogens significantly improve cognition of Alzheimer's disease mouse model by suppressing β-amyloid generation [10.1016/j.jff.2017.12.016] |
| Journal of Nutritional Biochemistry | Mechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet [Pubmed:29986309] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471] |
| Food Chem Toxicol | Effects of Alcohol Intake on Cognitive Function and ¦Â-amyloid Protein in APP/PS1 Transgenic Mice [33737111] |
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