脑源性神经营养因子(BDNF)真核蛋白
Eukaryotic Brain Derived Neurotrophic Factor (BDNF)
Neurotrophin; Abrineurin
- 编号UEPA011Hu61
- 物种Homo sapiens (Human,人) 相同的名称,不同的物种。
- 来源真核表达
- 宿主293F cell
- 内毒素水平<1.0EU per 1ug (determined by the LAL method)
- 亚细胞定位分泌
- 预测分子量-
- 实际分子量-(差异分析请参阅说明书)
- 片段与标签N-terminal His Tag
- 缓冲液成份磷酸盐缓冲液(pH7.4,含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.)
- 性状冻干粉
- 纯度> 90%
- 等电点-
- 
                    应用
                    Positive Control; Immunogen; SDS-PAGE; WB.
 如果需要有生物活性的蛋白,请参见活性蛋白。
- 下载 英文说明书 中文说明书
- 规格 10µg50µg 200µg 1mg 5mg
- 价格 ¥ 1440 ¥ 3600 ¥ 7200 ¥ 21600 ¥ 54000
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序列
 
                                
                            用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种:Homo sapiens (Human,人) | 应用(仅供研究使用,不用于临床诊断!) | 
| URPA011Hu04 | 脑源性神经营养因子(BDNF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPA011Hu05 | 脑源性神经营养因子(BDNF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPA011Hu03 | 脑源性神经营养因子(BDNF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPA011Hu01 | 脑源性神经营养因子(BDNF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPA011Hu02 | 脑源性神经营养因子(BDNF)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| UEPA011Hu62 | 脑源性神经营养因子(BDNF)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| UAPA011Hu01 | 脑源性神经营养因子(BDNF)活性蛋白 | Cell culture; Activity Assays. | 
| UAPA011Hu61 | 脑源性神经营养因子(BDNF)活性蛋白 | Cell culture; Activity Assays. | 
| UEPA011Hu61 | 脑源性神经营养因子(BDNF)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| UPAA011Hu01 | 脑源性神经营养因子(BDNF)多克隆抗体 | WB; IHC; ICC; IP. | 
| UPAA011Hu02 | 脑源性神经营养因子(BDNF)多克隆抗体 | WB | 
| UPAA011Hu06 | 脑源性神经营养因子(BDNF)多克隆抗体 | WB; IHC; ICC; IP. | 
| ULAA011Hu71 | 脑源性神经营养因子(BDNF)多克隆抗体(生物素标记) | WB; IHC; ICC. | 
| ULAA011Hu81 | 脑源性神经营养因子(BDNF)多克隆抗体(异硫氰酸荧光素标记) | WB; IHC; ICC; IF. | 
| UMAA011Hu23 | 脑源性神经营养因子(BDNF)单克隆抗体 | WB | 
| UMAA011Hu24 | 脑源性神经营养因子(BDNF)单克隆抗体 | WB | 
| UMAA011Hu22 | 脑源性神经营养因子(BDNF)单克隆抗体 | WB | 
| UMAA011Hu21 | 脑源性神经营养因子(BDNF)单克隆抗体 | ICC/IF | 
| USEA011Hu | 脑源性神经营养因子(BDNF)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| USCA011Hu | 脑源性神经营养因子(BDNF)检测试剂盒(化学发光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. | 
| ULMA011Hu | 脑源性神经营养因子(BDNF)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. | 
| UKSA011Hu01 | 脑源性神经营养因子(BDNF)检测试剂盒DIY材料(酶联免疫吸附试验法) | Main materials for "Do It (ELISA Kit) Yourself". | 
参考文献
| 杂志 | 参考文献 | 
| Toxicological Sciences | Interaction of PFOS and BDE-47 Co-exposure on Thyroid Hormone Levels and TH-Related Gene and Protein Expression in Developing Rat Brains [PubMed: 21436126] | 
| Journal of the Neurological Sciences | Neuroprotective effects of adipose-derived stem cells against ischemic neuronal damage in the rabbit spinal cord [ScienceDirect: S0022510X12001219] | 
| International Conference on Bioscience | Effect of Benthosemapterotum Peptide on Aging in Mice with Oxidative Damage [Psrcentre: 212059] | 
| Neuroscience Letters | Chronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice [ScienceDirect: S0304394010015788] | 
| BioMed Research International | Neuroprotective effects of adipose-derived stem cells are maintained for 3 weeks against ischemic damage in the rabbit spinal cord. [NCBI: PMC3925622] | 
| Behavioural Brain Research | The effects of Ginkgo biloba extract on cognitive functions in aged female rats: The role of oxidative stress and brain-derived neurotrophic factor [Pubmed:25446810] | 
| Neurochemical Research | Heme Oxygenase-1 Protects Neurons from Ischemic Damage by UpreCavia (Guinea pig )lating Expression of Cu,Zn-SuperoxideDismutase, Catalase, and Brain-Derived Neurotrophic Factor in the Rabbit Spinal Cord. [Pubmed:26559686] | 
| Exp Ther Med. | Effects of docosahexaenoic acid on learning and memory impairment induced by repeated propofol anesthesia in young rats [pmc:PMC4812310] | 
| Genet Mol Res | Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells [Pubmed:27323064] | 
| The International Journal af Applied Research in Veterinary Medicine | Effect of Sample Time in Clot Tube, Temperature, and Hemolysis Status on Canine Serum Brain-Derived Neurotrophic Factor (BDNF) Concentrations: Preliminary study [articles:Vol14Iss3] | 
| J Chem Neuroanat. | Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons. [pubmed:27914953] | 
| Int Immunopharmacol. | PPARr activation ameliorates postoperative cognitive decline probably through suppressing hippocampal neuroinflammation in aged mice. [pubmed:27940378] | 
| The Journal of Maternal-Fetal & Neonatal Medicine | Differential expression of cord blood neurotrophins in gestational diabetes: the impact of fetal growth abnormalities [pubmed:28081639] | 
| IOS Press Content Library | An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's … [articles:journal-of-alzheimers-disease] | 
| Bipolar Disorders | Long‐term lithium treatment increases intracellular and extracellular brain‐derived neurotrophic factor (BDNF) in cortical and hippocampal neurons at subtherapeutic … [bdi.12449] | 
| Elsevier | Associations of blood parameters with age, feed efficiency and sampling routine in young beef bulls [science:article] | 
| journal of allergy and clinical immunology | Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen–induced allergic rhinitis [pubmed:28412394] | 
| American Journal of Translational Research | A new comorbidity model and the common pathological mechanisms of migraine and epilepsy [pubmed:28559979] | 
| European Journal of Pharmacology | Alpha-asarone attenuates depression-like behavior in nicotine-withdrawn mice: Evidence for the modulation of hippocampal pCREB levels during nicotine-withdrawal. [pubmed:29042206] | 
| Brain, Behavior, and Immunity | An enriched environment restores hepatitis B vaccination-mediated impairments in synaptic function through IFN-γ/Arginase1 signaling [Pubmed:29627530] | 
| Stem Cell Research & Therapy | Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model [Pubmed:29335016] | 
| Pharmacological Research | N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype [Pubmed:29203442] | 
| Experimental Neurology | Preterm umbilical cord blood derived mesenchymal stem/stromal cells protect preterm white matter brain development against hypoxia-ischemia [Pubmed:30012511] | 
| Nutrients | Early Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model. [Pubmed:29890692] | 
| Neurotoxicity Research | Delta-9-Tetrahydrocannabinol (∆-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats [Pubmed:28933048] | 
| Neurotoxicology | Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats [Pubmed:29522778] | 
| Neuroscience Letters | Long term Westernized diet leads to region-specific changes in brain signaling mechanisms [Pubmed:29655945] | 
| Applied Physiology Nutrition and Metabolism | Changes in exercise capacity and serum BDNF following long-term sprint interval training in well-trained cyclists [Pubmed: 30286300] | 
| Heliyon | Establishment and evaluation of a novel mouse model of peri/postmenopausal depression [Doi: 10.1016/j.heliyon.2019.e01195] | 
| BioMed Research International | Administration of Repetitive Transcranial Magnetic Stimulation Attenuates Aβ1-42-Induced Alzheimer's Disease in Mice by Activating β-Catenin Signaling [] | 
| International Journal of Immunopathology and Pharmacology | Effect of voluntary running on expression of myokines in brains of rats with depression [Pubmed: 30834799] | 
| American Journal of Emergency Medicine | Clinical usefulness of brain-derived neurotrophic factor and visinin-like protein-1 in early diagnostic tests for acute stroke [Pubmed: 30826210] | 
| Neurochemistry International | Monoaminergic system is implicated in the antidepressant-like effect of hyperoside and protocatechuic acid isolated from Impatiens glandulifera Royle in mice [Pubmed: 31077758] | 
| REVISTA DA ASSOCIACAO MEDICA BRASILEIRA | Physical Exercise Increased Brain-Derived Neurotrophic Factor in Elderly Population with Depression [Pubmed: 30994834] | 
| Journal of Alzheimer's Disease | Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice [Pubmed: 31561359] | 
| Biological Trace Element Research | Cognitive Decline of Rats with Chronic Fluorosis Is Associated with Alterations in Hippocampal Calpain Signaling [Pubmed: 31797207] | 
| Psychopharmacology | Chronic harmine treatment has a delayed effect on mobility in control and socially defeated rats [Pubmed: 32088835] | 
| Experimental and Therapeutic Medicine | Involvement of neurotrophic signaling in doxorubicin‑induced cardiotoxicity [Pubmed: 32010279] | 
| Journal of Critical Care | Association of neuronal repair biomarkers with delirium among survivors of critical illness [Pubmed: 31896448] | 
| Journal of Clinical Neuroscience | CSF levels of a set of neurotrophic factors (brain-derived neurotrophic factor, nerve growth factor) and neuropeptides (neuropeptide Y, galanin) in epileptic children [Pubmed: 32327377] | 
| MOLECULAR NUTRITION & FOOD RESEARCH | Hyperlipidemia Down‐Regulate Brain Antioxidant Defense Enzymes and Neurotrophins in Rats: Assessment of the Modulatory Potential of EPA+ DHA and … [Pubmed: 32918393] | 
| Neuropharmacology | Impaired LTD-like motor cortical plasticity in female patients with major depression disorder [Pubmed: 32791084] | 
| COLLOIDS AND SURFACES B-BIOINTERFACES | Effects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of parkinson's disease [Pubmed: 32777662] | 
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471] | 
| Journal of Veterinary Behavior | Comparison of serum brain-derived neurotrophic factor (BDNF) in dogs with and without separation anxiety [] | 
| Food & Function | Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial … [] | 
| Short-but no long-term effect of social stress in rodent depressive-like behavior is not affected by chronic treatment with Harmine [] | |
| bioinformatics and biomedical engineering | Blood Plasma Trophic Growth Factors Predict the Outcome in Patients with Acute Ischemic Stroke [] | 
| Overektomize dişi sıçanlarda beyin oksidatif stres, bdnf ve inflamatuar cevap düzeyleri ile nörodavranışsal değişiklikler üzerine anjiyotensin II İnhibisyonunun etkisi [] | |
| EUROPEAN CHILD & ADOLESCENT PSYCHIATRY | Increased serum brain-derived neurotrophic factor and adrenocorticotropic hormone levels are associated with obsessive compulsive disorder in medication?free?¡ [33389158] | 
| BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | Sea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways [33589896] | 
| Neuropsychiatr Dis Treat | Repetitive Transcranial Magnetic Stimulation Improves Mild Cognitive Impairment Associated with Alzheimer's Disease in Mice by Modulating the miR-567 … [34239303] | 
| Einstein (Sao Paulo) | Tropomyosin receptor kinase B-mediated signaling in integration of neuropathic pain and obesity in diabetic polyneuropathy [34586159] | 
| Metab Brain Dis | Moderate-intensity continuous training and high-intensity interval training improve cognition, and BDNF levels of middle-aged overweight men [34762211] | 
| Transl Psychiatry | Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression [34824208] | 
| Iranian Journal of Basic Medical Sciences | Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [34712429] | 
| J Sex Med | Endogenous Deficiency of Brain-Derived Neurotrophic Factor Induces the Downregulation of Tryptophan Hydroxylase-2 Expression in Raphe Nuclei of Rapid … [34384732] | 
| Cell Biochem Funct | CNTs‐CaP/chitosan‐coated AZ91D magnesium alloy extract promoted rat dorsal root ganglia neuron growth via activating ERK signalling pathway [34296452] | 
| J Endocrinol Invest | Serum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader … [Pubmed:35098494] | 
| Clinical Rheumatology | Gender influence on clinical manifestations, depressive symptoms and brain-derived neurotrophic factor (BDNF) serum levels in patients affected by … [Pubmed:35344113] | 
| Sci Rep | Associations between serum levels of brain-derived neurotrophic factor, corticotropin releasing hormone and mental distress in vitiligo patients [Pubmed:35508633] | 
| Pharmaceutics | Co-Delivery of Docosahexaenoic Acid and Brain-Derived Neurotropic Factor from Electrospun Aligned Core–Shell Fibrous Membranes in Treatment of Spinal Cord … [Pubmed:35214053] | 
| Molecular Biology Reports | Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling … [Pubmed:35585377] | 
| Journal of Complementary Medicine Research | Effect of herbal formulation Sharbat Ahmad Shahi on serum BDNF level in mild to moderate cases of depressive disorder [] | 
| AFRICAN JOURNAL OF BIOCHEMISTRY RESEARCH | Medicinal effects of Saffron on obese animals by reducing Castellis risk index to protect from cardio-pathology and psychological distress [] | 
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