尿激酶型纤溶酶原激活因子(uPA)重组蛋白
Recombinant Plasminogen Activator, Urokinase (uPA)
PLAU; ATF; URK; UK; UP-A; Abbokinase; Urokinase-Type Plasminogen Activator
- 编号URPA140Po02
 - 物种Sus scrofa; Porcine (Pig,猪) 相同的名称,不同的物种。
 - 来源原核表达
 - 宿主E.coli
 - 内毒素水平<1.0EU/µg(LAL法测定)
 - 亚细胞定位分泌
 - 预测分子量30.1kDa
 - 实际分子量33kDa(差异分析请参阅说明书)
 - 片段与标签Ser21~Pro168 with Two N-terminal Tags, His-tag and SUMO-tag
 - 缓冲液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
 - 性状冻干粉
 - 纯度> 95%
 - 等电点8.7
 - 
                    应用
                    Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,请参见活性蛋白。 - 下载 英文说明书 中文说明书
 - 规格 10µg50µg 200µg 1mg 5mg
 - 价格 ¥ 628 ¥ 1569 ¥ 3138 ¥ 9414 ¥ 23535
 - 欲了解实际交易价格和更多情况,请与当地经销商联系!
 
序列
                                
                            用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
储存
避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。
稳定性
热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。
增值服务
相关产品
| 编号 | 适用物种:Sus scrofa; Porcine (Pig,猪) | 应用(仅供研究使用,不用于临床诊断!) | 
| URPA140Po01 | 尿激酶型纤溶酶原激活因子(uPA)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPA140Po02 | 尿激酶型纤溶酶原激活因子(uPA)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| URPA140Po03 | 尿激酶型纤溶酶原激活因子(uPA)重组蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
| UPAA140Po01 | 尿激酶型纤溶酶原激活因子(uPA)多克隆抗体 | WB; IHC; ICC; IP. | 
| UMAA140Po21 | 尿激酶型纤溶酶原激活因子(uPA)单克隆抗体 | WB; IHC; ICC; IP. | 
| USEA140Po | 尿激酶型纤溶酶原激活因子(uPA)检测试剂盒(酶联免疫吸附试验法) | Enzyme-linked immunosorbent assay for Antigen Detection. | 
| ULMA140Po | 尿激酶型纤溶酶原激活因子(uPA)等多因子检测试剂盒(流式荧光发光法) | FLIA Kit for Antigen Detection. | 
参考文献
| 杂志 | 参考文献 | 
| Breast Cancer Research and Treatment | Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice [SpringerLink: f3w831267267p277] | 
| Biomarker insights | Decreased Hepatocyte Growth Factor (HGF) and Gamma Aminobutyric Acid (GABA) in Individuals with Obsessive-Compulsive Disorder (OCD) [PubMed: PMC3762604] | 
| Oncol Rep. | Downregulation of MACC1 inhibits invasion, migration and proliferation, attenuates cisplatin resistance and induces apoptosis in tongue squamous cell carcinoma [Pubmed:25421538] | 
| International Journal of Oncology | 1, 25-Dihydroxyvitamin D3 alleviates salivary adenoid cystic carcinoma progression by suppressing GPX1 expression through the NF-κB pathway [Pubmed:26782341] | 
| Biochemical and Biophysical Research Communications | Methylation of neurofilament light polypeptide promoter is associated with cell invasion and metastasis in NSCLC [Pubmed:26801564] | 
| 39 | Cytokine and Estrogen Stimulation of Endothelial Cells Augments Activation of the Surface-Bound Prekallikrein-High Molecular Weight Kininogen Complex: Implications for Hereditary Angioedema (HAE): 814 [article:S0091-6749(15)02643-3] | 
| SCIENCE & TECHNOLOGY | A Study Protocol: Spinal Morphology, Physical Performance, Quality of Life and Biochemical Markers in Adults at Risk of Osteoporotic Fractures [59f7c85aaca272607e2d8d7a] | 
| Oncotarget | Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma [pubmed:28404945] | 
| Journal of allergy and clinical immunology | Cytokine and estrogen stimulation of endothelial cells augments activation of the prekallikrein-high molecular weight kininogen complex: Implications for hereditary angioedema. [pubmed:27826093] | 
| Molecular Medicine Reports | Effect of a synthetic inhibitor of urokinase plasminogen activator on the migration and invasion of human cervical cancer cells in vitro [Pubmed:29328476] | 
| Phytomedicine | Multi-omics analysis reveals the mechanisms of action and therapeutic regimens of traditional Chinese medicine, Bufei Jianpi granules: Implication for COPD drug … [Pubmed:35121390] | 
| Cellular and Molecular Life Sciences | IL4 stimulated macrophages promote axon regeneration after peripheral nerve injury by secreting uPA to stimulate uPAR upregulated in injured axons [Pubmed:35536429] | 
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