分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记)

Biotin-Linked Polyclonal Antibody to Secreted Frizzled Related Protein 5 (SFRP5)

SARP3; Secreted Apoptosis Related Protein 3; Frizzled-related protein 1b

  • 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记) 产品包装(模拟)
  • 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记) 产品包装(模拟)
  • PAC842Ra71.jpg WB图
  • Certificate 通过ISO 9001、ISO 13485质量体系认证

特异性

该抗体是针对SFRP5的兔多克隆抗体。在免疫组织化学染色和免疫印迹实验中能识别SFRP5。

用法

免疫印迹:0.2-2µg/mL;1:250-2500
免疫组织化学:5-20µg/mL;1:25-100
免疫细胞化学:5-20µg/mL;1:25-100
最佳稀释倍数最终由用户决定。

储存

经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。

稳定性

热稳定性以损失率显示。损失率是由加速降解试验决定,具体方法如下:在37°C孵育48小时,没有显著的降解或者沉淀产生。保质期内,在适当的条件下存储,损失率低于5%。

相关产品

编号 适用物种:Rattus norvegicus (Rat,大鼠) 应用(仅供研究使用,不用于临床诊断!)
RPC842Ra01 分泌型卷曲相关蛋白5(SFRP5)重组蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAC842Ra01 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体 WB; IHC; ICC; IP.
LAC842Ra71 分泌型卷曲相关蛋白5(SFRP5)多克隆抗体(生物素标记) WB; IHC; ICC.
MAC842Ra21 分泌型卷曲相关蛋白5(SFRP5)单克隆抗体 WB; IHC; ICC; IP.
SEC842Ra 分泌型卷曲相关蛋白5(SFRP5)检测试剂盒(酶联免疫吸附试验法) Enzyme-linked immunosorbent assay for Antigen Detection.

参考文献

杂志 参考文献
Diabetes Research and Clinical Practice Plasma SFRP5 levels are decreased in Chinese subjects with obesity and type 2 diabetes and negatively correlated with parameters of insulin resistance [PubMed: 23290274]
European Journal of Clinical Investigation Sfrp5 correlates with insulin resistance and oxidative stress [PubMed: 23398169]
Pediatric Research Balanced duo of anti-inflammatory SFRP5 and proinflammatory WNT5A in children [Pubmed: 24603290]
Clin Endocrinol (Oxf). SFRP5 correlates with obesity and metabolic syndrome and increases after weight loss in children [Pubmed: 24330025]
The Journal of Clinical Endocrinology & Metabolism Circulating Sfrp5 is a signature of obesity-related metabolic disorders and is regulated by glucose and liraglutide in humans [Pubmed: 23185036]
Atherosclerosis Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease [Pubmed: 24530778]
PLoS One. Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation [Pubmed:Pmc4072672]
J Clin Endocrinol Metab. Activation of noncanonical Wnt signaling through WNT5A in visceral adipose tissue of obese subjects is related to inflammation [Pubmed:24840810]
Oncology Letters Serum secreted frizzled?related protein 5 levels differentially decrease in patients with hepatitis B virus?associated chronic infection and hepatocellular carcinoma [Pubmed:25120720]
Diabetes Metab Res Rev. Circulating SFRP5 levels are elevated in drug‐na?ve recently diagnosed type 2 diabetic patients as compared with prediabetic subjects and controls [Pubmed:25139699]
Clinical & Experimental Immunology The wingless-related integration site-5a/secreted frizzled-related protein-6 system is dysregulated in human sepsis [Pubmed:25382802]
Diabetes Metab Res Rev Circulating SFRP5 levels are elevated in drug-na [PubMed: 25139699]
J Matern Fetal Neonatal Med Prediction of gestational diabetes mellitus by first trimester serum secreted frizzle-related protein-5 levels [PubMed: 26100762]
Eur J Clin Invest Sfrp5 associates with beta-cell function in humans [Pubmed:27019073]
Osteoporosis International Bone marrow sFRP5 level is negatively associated with bone formation markers [pubmed:27986984]
Diabetes/Metabolism Research and Reviews Plasma Sfrp5 levels correlate with determinants of the metabolic syndrome in Chinese adults [pubmed:28303637]
Cardiovascular Diabetology Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study [pubmed:28851362]
Arteriosclerosis, Thrombosis, and Vascular Biology  Effect of SFRP5 (Secreted Frizzled–Related Protein 5) on the WNT5A (Wingless-Type Family Member 5A)-Induced Endothelial Dysfunction and Its Relevance With … [Pubmed:29674475]
Obesity Longitudinal Increases in Adiposity Contribute to Worsening Adipokine Profile over Time in Mexican Americans [Pubmed:29427376]
J Bas Res Med Sci Decreased level of the anti-inflammatory adipokines, secreted frizzled-related protein 5 and adiponectin, in high cholesterol diet-induced atherosclerotic rats [article-1-352-en.pdf]
Molecular Biology Reports The effect of serum and follicular fluid secreted frizzle-related protein-5 on in vitro fertilization outcomes in patients with polycystic ovary syndrome [Pubmed: 30194556]
Macrophage LRP1 promotes diet-induced hepatic inflammation and metabolic dysfunction by modulating Wnt signaling []
British Journal Of Nutrition A diet high in sugar-sweetened beverage and low in fruits and vegetables is associated with adiposity and a pro-inflammatory adipokine profile [Pubmed: 30375290]
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